Chromosomal abnormalities in bronchial epithelium from smokers, nonsmokers, and lung cancer patients
Slebos RJ, Livanos E, Yim HW, Randell SH, Parsons AM, Detterbeck FC, Rivera MP, Taylor JA. Chromosomal abnormalities in bronchial epithelium from smokers, nonsmokers, and lung cancer patients. Cancer Genetics 2005, 159: 137-142. PMID: 15899385, DOI: 10.1016/j.cancergencyto.2004.10.008.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBronchiCells, CulturedChildChromosome AberrationsEpithelial CellsFemaleHumansKaryotypingLung NeoplasmsMaleMiddle AgedSmokingTumor Cells, CulturedConceptsLung cancer patientsCancer patientsNon-lung cancer patientsAbnormal metaphasesChromosomal abnormalitiesHistory of smokingTobacco smoke exposureBronchial epithelial cell culturesHBE cell culturesCell culturesHuman bronchial epithelial cell culturesTobacco smokingSmoke exposureLung cancerEarly treatmentBronchial epitheliumCancer riskIdentification of individualsEpithelial cell culturesPatientsNonsmokersUseful markerGreater riskSmokersObserved abnormalities