2018
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlgorithmsFemaleFluorodeoxyglucose F18HumansLung NeoplasmsMaleMiddle AgedPositron-Emission TomographyRadiation DosageRadiopharmaceuticalsROC CurveSolitary Pulmonary NoduleConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2017
Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database
Korst RJ, Fernando S, Catlin AC, Rutledge JR, Girard N, Huang J, Detterbeck F, Database C. Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database. The Annals Of Thoracic Surgery 2017, 104: 1815-1820. PMID: 29033016, PMCID: PMC5785101, DOI: 10.1016/j.athoracsur.2017.06.053.Peer-Reviewed Original ResearchConceptsPositron emission tomographyInternational Thymic Malignancy Interest GroupHistologic typeThymic malignanciesPretreatment workupPathologic stageEmission tomographyProspective databaseThymic tumorsTumor stageMaximum standardized uptake valueProspective research databaseHistologic tumor typeThymic epithelial tumorsStandardized uptake valueCharacteristic curveAnalysis of receiverClinicopathologic featuresRare tumorEpithelial tumorsLarge cohortResearch DatabaseUptake valueTumor typesPatients
2015
Viewing Lung Cancer in Color Instead of Black and White
Detterbeck FC. Viewing Lung Cancer in Color Instead of Black and White. Annals Of The American Thoracic Society 2015, 12: 1118-9. PMID: 26317270, DOI: 10.1513/annalsats.201506-338ed.Peer-Reviewed Original ResearchAdenocarcinomaFemaleHumansLung NeoplasmsMaleMedical OverusePositron-Emission TomographyTomography, X-Ray Computed
2013
Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC. Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e211s-e250s. PMID: 23649440, DOI: 10.1378/chest.12-2355.Peer-Reviewed Original ResearchConceptsLung cancerPET scanningNeedle techniqueCT scanningMediastinal metastasesMetastatic diseasePractice guidelinesAmerican CollegeChest Physicians Evidence-Based Clinical Practice GuidelinesTissue biopsiesChest Physicians Lung Cancer GuidelinesEvidence-based clinical practice guidelinesNon-small cell lung cancer diagnosisNon-small cell lung cancerMediastinal lymph node metastasisCell lung cancer diagnosisLung cancer guidelinesPET scan findingsLymph node metastasisCell lung cancerClinical practice guidelinesLymph node stationsUnsuspected metastatic diseaseEndobronchial ultrasound needle aspirationPET-CT scanning
2012
Thoroughness of Mediastinal Staging in Stage IIIA Non-small Cell Lung Cancer
Vest MT, Tanoue L, Soulos PR, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Thoroughness of Mediastinal Staging in Stage IIIA Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2012, 7: 188-195. PMID: 22134069, PMCID: PMC3253367, DOI: 10.1097/jto.0b013e318236ecbb.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiopsy, NeedleCarcinoma, Non-Small-Cell LungCohort StudiesComorbidityConfidence IntervalsGuideline AdherenceHumansLung NeoplasmsLymph NodesMediastinoscopyMediastinumMedicareMultivariate AnalysisNeoplasm StagingOdds RatioPositron-Emission TomographySEER ProgramSurvival AnalysisUnited StatesConceptsStage IIIA non-small cell lung cancerIIIA non-small cell lung cancerNon-small cell lung cancerInvasive stagingCell lung cancerMediastinal stagingLung cancerClinical stage IIIA non-small cell lung cancerEnd Results-Medicare databaseStage IIIA NSCLC patientsPositron emission tomography scanningPathologic lymph nodesIIIA NSCLC patientsMultivariable logistic regressionInvasive mediastinal stagingNSCLC patientsOlder patientsPatient characteristicsLymph nodesPatient factorsHistologic confirmationPractice patternsMedicare claimsMedicare beneficiariesPET scanning
2011
Approach to the Ground-Glass Nodule
Detterbeck FC, Homer RJ. Approach to the Ground-Glass Nodule. Clinics In Chest Medicine 2011, 32: 799-810. PMID: 22054887, DOI: 10.1016/j.ccm.2011.08.002.Peer-Reviewed Original ResearchMeSH KeywordsHumansLung NeoplasmsMultiple Pulmonary NodulesPneumonectomyPositron-Emission TomographyRisk FactorsSolitary Pulmonary NoduleTomography, X-Ray ComputedWatchful Waiting
2010
Imaging Requirements in the Practice of Pulmonary Metastasectomy
Detterbeck FC, Grodzki T, Gleeson F, Robert JH. Imaging Requirements in the Practice of Pulmonary Metastasectomy. Journal Of Thoracic Oncology 2010, 5: s134-s139. PMID: 20502248, DOI: 10.1097/jto.0b013e3181dcf64d.Peer-Reviewed Original ResearchMeSH KeywordsFollow-Up StudiesHumansLung NeoplasmsPalpationPneumonectomyPositron-Emission TomographyRadiography, ThoracicTomography, Spiral ComputedTomography, X-Ray ComputedConceptsHelical CT scansPulmonary metastasectomyCT scanThin-section scanningBetter patient selectionPrimary imaging modalityPositron emission tomographyPulmonary metastasesFurther metastasesMetastatic sitesPatient selectionSurveillance imagingPeriod of observationEmission tomographyMetastasisImaging modalitiesMetastasectomyReconstruction thicknessPatientsTomographyScansOptimal intervalFollowPalpationWeeksA Systematic Review but Systematically Confounded?
Detterbeck FC. A Systematic Review but Systematically Confounded? Journal Of Thoracic Oncology 2010, 5: 754-756. PMID: 20421774, DOI: 10.1097/jto.0b013e3181d3524d.Peer-Reviewed Original ResearchA Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage
de Cabanyes Candela S, Detterbeck FC. A Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage. Journal Of Thoracic Oncology 2010, 5: 389-398. PMID: 20186025, DOI: 10.1097/jto.0b013e3181ce3e5e.Peer-Reviewed Original ResearchConceptsInduction therapyPositron emission tomographyLung cancerComputed tomographySystematic reviewStage IIIA lung cancerEmission tomographyIIIA lung cancerMediastinal node involvementRepeat mediastinoscopyNode involvementComplete responsePathologic findingsEsophageal ultrasoundPathologic stageNeedle aspirationExpert handsRestagingFalse negative rateMediastinoscopyTherapyFN rateTomographyPatientsSurgery
2009
Invited Commentary
Detterbeck F. Invited Commentary. The Annals Of Thoracic Surgery 2009, 87: 378. PMID: 19161741, DOI: 10.1016/j.athoracsur.2008.12.040.Peer-Reviewed Original ResearchBiopsy, Fine-NeedleCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsMalePositron-Emission TomographySensitivity and Specificity
2007
Noninvasive Staging of Non-small Cell Lung Cancer ACCP Evidenced-Based Clinical Practice Guidelines (2nd Edition)
Silvestri GA, Gould MK, Margolis ML, Tanoue LT, McCrory D, Toloza E, Detterbeck F. Noninvasive Staging of Non-small Cell Lung Cancer ACCP Evidenced-Based Clinical Practice Guidelines (2nd Edition). CHEST Journal 2007, 132: 178s-201s. PMID: 17873168, DOI: 10.1378/chest.07-1360.Peer-Reviewed Original ResearchConceptsChest CT scanningPET scanningCT scanningMediastinal metastasesMetastatic diseaseStaging studiesLung cancerPractice guidelinesLung Cancer ACCP Evidence-Based Clinical Practice GuidelinesACCP Evidence-Based Clinical Practice GuidelinesEvidence-based clinical practice guidelinesMediastinal lymph node metastasisPositron emission tomography scanningTest characteristicsLung cancer guidelinesDistant metastatic diseaseLymph node metastasisClinical practice guidelinesMalignant lymph nodesNoninvasive imaging studiesAbnormal findingsCancer guidelinesLymph nodesNode metastasisAccurate stagingEvolution and science, progress and change
Detterbeck FC. Evolution and science, progress and change. Thorax 2007, 62: 654. PMID: 17687093, PMCID: PMC2117279, DOI: 10.1136/thx.2007.077594.Peer-Reviewed Original ResearchCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsLymphatic MetastasisNeoplasm StagingPositron-Emission Tomography
2006
Positron emission tomographic scanning in the diagnosis and staging of non–small cell lung cancer 2 cm in size or less
Khandani AH, Detterbeck FC. Positron emission tomographic scanning in the diagnosis and staging of non–small cell lung cancer 2 cm in size or less. Journal Of Thoracic And Cardiovascular Surgery 2006, 132: 214-215. PMID: 16798357, DOI: 10.1016/j.jtcvs.2006.01.057.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsNeoplasm StagingPositron-Emission Tomography
2005
Relearning the Lessons of the Past: Are We Making Progress?
Detterbeck FC. Relearning the Lessons of the Past: Are We Making Progress? The Annals Of Thoracic Surgery 2005, 80: 1979-1980. PMID: 16242512, DOI: 10.1016/j.athoracsur.2005.03.046.Peer-Reviewed Original ResearchCarcinoma, Non-Small-Cell LungHumansLung NeoplasmsMediastinoscopyPositron-Emission TomographyTomography, X-Ray Computed
2004
Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer
Detterbeck FC, Vansteenkiste JF, Morris DE, Dooms CA, Khandani AH, Socinski MA. Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer. CHEST Journal 2004, 126: 1656-1666. PMID: 15539740, DOI: 10.1378/chest.126.5.1656.Peer-Reviewed Original ResearchMeSH KeywordsCombined Modality TherapyHumansLung NeoplasmsNeoplasm StagingPositron-Emission TomographyPredictive Value of TestsPrognosisReproducibility of ResultsConceptsManagement of patientsLung cancerPET imagingCycles of chemotherapyCompletion of treatmentPossible lung cancerIntensity of uptakePositron emission tomography (PET) imagingEmission Tomography ImagingPositron emission tomographyFurther technologic improvementsInduction therapyPatient outcomesBiological aggressivenessPatientsEmission tomographyTechnologic improvementsTomography imagingStaging approachRadiotherapy treatment fieldCancerTreatment fieldImagingTreatmentPET images