2020
Radiation Therapy for Small Cell Lung Cancer: An ASTRO Clinical Practice Guideline
Simone CB, Bogart JA, Cabrera AR, Daly ME, DeNunzio NJ, Detterbeck F, Faivre-Finn C, Gatschet N, Gore E, Jabbour SK, Kruser TJ, Schneider BJ, Slotman B, Turrisi A, Wu AJ, Zeng J, Rosenzweig KE. Radiation Therapy for Small Cell Lung Cancer: An ASTRO Clinical Practice Guideline. Practical Radiation Oncology 2020, 10: 158-173. PMID: 32222430, PMCID: PMC10915746, DOI: 10.1016/j.prro.2020.02.009.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerStereotactic body radiation therapyProphylactic cranial irradiationES-SCLCCell lung cancerThoracic RTLS-SCLCLung cancerRadiation therapyExtensive-stage (ES) SCLCNode-negative small cell lung cancerStage IASTRO Clinical Practice GuidelineInvolved field RTRadiation oncologist consultationStage I patientsNode-negative diseaseClinical practice guidelinesRadiation Oncology guidelinesBody radiation therapyCourse of treatmentGood clinical practiceAmerican SocietyAdvanced treatment modalitiesAdjuvant RT
2019
Lung Cancer Surveillance After Definitive Curative-Intent Therapy: ASCO Guideline.
Schneider BJ, Ismaila N, Aerts J, Chiles C, Daly ME, Detterbeck FC, Hearn JWD, Katz SI, Leighl NB, Levy B, Meyers B, Murgu S, Nekhlyudov L, Santos ES, Singh N, Tashbar J, Yankelevitz D, Altorki N. Lung Cancer Surveillance After Definitive Curative-Intent Therapy: ASCO Guideline. Journal Of Clinical Oncology 2019, 38: 753-766. PMID: 31829901, DOI: 10.1200/jco.19.02748.Peer-Reviewed Original ResearchConceptsCurative-intent therapyLung cancerStage IFluorodeoxyglucose positron emission tomography/Evidence-based guideline recommendationsNew primary lung cancerRetrospective comparative observational studySurveillance strategiesSmall cell lung cancerBrain magnetic resonance imagingLiterature searchPositron emission tomography/Lung cancer surveillanceCurative-intent treatmentPrimary lung cancerRecurrence-free survivalCell lung cancerDetection of recurrenceComparative observational studyEmission tomography/Optimal imaging modalityEvidence-based recommendationsOutcomes of interestQuality of lifeMagnetic resonance imaging
2016
Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery
Thomas DC, Arnold BN, Rosen JE, Salazar MC, Blasberg JD, Detterbeck FC, Boffa DJ, Kim AW. Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery. Lung Cancer 2016, 103: 75-81. PMID: 28024700, DOI: 10.1016/j.lungcan.2016.11.016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantCombined Modality TherapyDatabases, FactualFemaleGuidelines as TopicHumansLung NeoplasmsLymphatic MetastasisMaleMiddle AgedNeoplasm StagingOutcome Assessment, Health CarePneumonectomyPostoperative PeriodRadiotherapySmall Cell Lung CarcinomaSurvival AnalysisConceptsStage I small cell lung cancerClinical stage ISmall cell lung cancerCell lung cancerAdjuvant chemotherapySurgical resectionPathologic upstagingStage IRadiation therapyNodal diseaseLung cancerPositive lymph node involvementNational Cancer DatabaseOutcomes of patientsLymph node involvementProportion of patientsCurative intentNodal upstagingSCLC patientsUpstaged patientsAdjuvant therapyNode involvementIndependent predictorsInferior survivalT descriptor
2015
Bolstering the Case for Lobectomy in Stages I, II, and IIIA Small-Cell Lung Cancer Using the National Cancer Data Base
Combs SE, Hancock JG, Boffa DJ, Decker RH, Detterbeck FC, Kim AW. Bolstering the Case for Lobectomy in Stages I, II, and IIIA Small-Cell Lung Cancer Using the National Cancer Data Base. Journal Of Thoracic Oncology 2015, 10: 316-323. PMID: 25319182, DOI: 10.1097/jto.0000000000000402.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerNational Cancer Data BaseSurgical resectionStage ISCLC patientsSublobar resectionOverall survivalLung cancerIIIA small cell lung cancerFive-year overall survivalAddition of surgeryClinical stage IPatient underwent surgeryPrimary surgical resectionKaplan-Meier methodLikelihood of deathCurative intentComorbidity scoreUnderwent surgeryChemoradiation therapyHazard ratioMetastatic diseaseMultimodality treatmentSelect patientsTreatment regimen
2014
Clinical Presentation and Evaluation of Neuroendocrine Tumors of the Lung
Detterbeck FC. Clinical Presentation and Evaluation of Neuroendocrine Tumors of the Lung. Thoracic Surgery Clinics 2014, 24: 267-276. PMID: 25065927, DOI: 10.1016/j.thorsurg.2014.04.002.Peer-Reviewed Original ResearchConceptsCell lung cancerCarcinoid tumorsLung cancerNeuroendocrine tumorsLimited biopsyNon-small cell lung cancerLarge cell neuroendocrine cancerMost non-small cell lung cancersSmall cell lung cancerPeripheral parenchymal lesionAtypical carcinoid tumorTypical carcinoid tumorNode enlargementEndobronchial tumorMediastinal tumorCharacteristic presentationClinical presentationParenchymal lesionsNeuroendocrine cancerRapid progressionTumorsCancerBiopsyLungPresentation
2010
Surveillance Epidemiology and End Results Evaluation of the Role of Surgery for Stage I Small Cell Lung Cancer
Yu JB, Decker RH, Detterbeck FC, Wilson LD. Surveillance Epidemiology and End Results Evaluation of the Role of Surgery for Stage I Small Cell Lung Cancer. Journal Of Thoracic Oncology 2010, 5: 215-219. PMID: 20101146, DOI: 10.1097/jto.0b013e3181cd3208.Peer-Reviewed Original ResearchConceptsStage I small cell lung cancerSmall cell lung cancerCell lung cancerRadiation therapyOverall survivalSurveillance EpidemiologyLung cancerStage INational Cancer Institute's Surveillance EpidemiologyUse of RTKaplan-Meier survival curvesEnd-result evaluationCancer-directed surgeryRole of surgeryStage I patientsEnd Results (SEER) databaseType of surgeryChemotherapy detailsSEER databaseSpecific survivalSystemic therapyI patientsMargin statusMedian ageClinical outcomes
2004
Systematic Review Evaluating the Timing of Thoracic Radiation Therapy in Combined Modality Therapy for Limited-Stage Small-Cell Lung Cancer
Fried DB, Morris DE, Poole C, Rosenman JG, Halle JS, Detterbeck FC, Hensing TA, Socinski MA. Systematic Review Evaluating the Timing of Thoracic Radiation Therapy in Combined Modality Therapy for Limited-Stage Small-Cell Lung Cancer. Journal Of Clinical Oncology 2004, 22: 4837-4845. PMID: 15570087, DOI: 10.1200/jco.2004.01.178.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantCombined Modality TherapyConfidence IntervalsDose Fractionation, RadiationDose-Response Relationship, RadiationHumansLung NeoplasmsNeoplasm StagingOdds RatioPneumonectomyPrognosisRadiotherapy DosageRadiotherapy, AdjuvantRandomized Controlled Trials as TopicRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsThoracic radiation therapyPlatinum-based chemotherapyRisk ratioRadiation therapyLS-SCLCLung cancerLimited-stage small cell lung cancerSmall cell lung cancerHyperfractionated radiation therapyLimited-Stage SmallProphylactic cranial irradiationCombined modality therapyCell lung cancerCranial irradiationChemotherapy regimensChemotherapeutic regimenModality therapySurvival benefitRandomized trialsDaily fractionationSubset analysisRadiation fractionationRT relativeRisk differenceChemotherapy
2003
Invasive Staging of Non-small Cell Lung Cancer* A Review of the Current Evidence
Toloza EM, Harpole L, Detterbeck F, McCrory DC. Invasive Staging of Non-small Cell Lung Cancer* A Review of the Current Evidence. CHEST Journal 2003, 123: 157s-166s. PMID: 12527575, DOI: 10.1378/chest.123.1_suppl.157s.Peer-Reviewed Original ResearchConceptsEndoscopic ultrasound-guided needle aspirationNon-small cell lung cancerTransbronchial needle aspirationTransthoracic needle aspirationCell lung cancerNegative predictive valueStandard cervical mediastinoscopyLung cancerCervical mediastinoscopyNeedle aspirationComorbid illnessesPooled sensitivitySmall cell lung cancerPooled specificityUltrasound-guided needle aspirationCochrane Library databasesTest performance characteristicsDegree of suspicionInvasive stagingAnterior mediastinotomyMetastatic diseaseClinical stagingHistologic confirmationCurrent evidenceLibrary databases