2018
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2004
Accuracy of Helical CT in the Detection of Pulmonary Metastases: Is Intraoperative Palpation Still Necessary?
Parsons AM, Detterbeck FC, Parker LA. Accuracy of Helical CT in the Detection of Pulmonary Metastases: Is Intraoperative Palpation Still Necessary? The Annals Of Thoracic Surgery 2004, 78: 1910-1918. PMID: 15561000, DOI: 10.1016/j.athoracsur.2004.05.065.Peer-Reviewed Original ResearchConceptsConventional computed tomographyLung palpationPulmonary metastasectomyIntraoperative palpationMore malignant nodulesDisease-free intervalMalignant nodulesPrimary outcome measureConventional CTExtrathoracic malignanciesMetastasectomy patientsCurative intentPulmonary metastasesMore metastasesRetrospective reviewTumor histologyDetectable diseaseIntraparenchymal nodulesMultiple lesionsSubset analysisMedical recordsOutcome measuresSingle lesionComputed tomographyMetastasectomy