Differential Integrin Adhesome Expression Defines Human NK Cell Residency and Developmental Stage.
Hegewisch-Solloa E, Seo S, Mundy-Bosse BL, Mishra A, Waldman EH, Maurrasse S, Grunstein E, Connors TJ, Freud AG, Mace EM. Differential Integrin Adhesome Expression Defines Human NK Cell Residency and Developmental Stage. The Journal Of Immunology 2021, 207: 950-965. PMID: 34282002, PMCID: PMC8324558, DOI: 10.4049/jimmunol.2100162.Peer-Reviewed Original ResearchConceptsActin regulating proteinsDevelopmental stagesNK cellsCell developmental stagesHuman hematopoietic precursorsActin homeostasisPeripheral bloodSignaling interactionsHuman NK cell populationsMolecular networksExpression profilesDifferential expressionNK cell populationVaried microenvironmentsInnate immune cellsRegulating proteinsVariety of microenvironmentsHematopoietic precursorsAdhesomeActin contentCell coculture systemCell populationsImmune cellsExpressionProtein