Signature of Enhanced Effector Function Defines Early Life Regulatory T Cells
Connors T, Bradley M, Verma S, Waldman E, Jang M, Grunstein E, Maurrasse S, Pethe K, Dogra P, Farber D. Signature of Enhanced Effector Function Defines Early Life Regulatory T Cells. The Journal Of Immunology 2021, 206: 98.27-98.27. DOI: 10.4049/jimmunol.206.supp.98.27.Peer-Reviewed Original ResearchRegulatory T cellsT cellsImmune responseEarly lifeGut-specific homingPrimary antigenic challengeIntestinal immune homeostasisConventional T cellsPotential effector mechanismsInflammatory immune responseEnhanced effector functionMulti-parameter flow cytometryAdult TregsImmunosuppressive mechanismsAntigenic challengeImmune homeostasisEffector mechanismsTregsImmune developmentEffector functionsSuppressive functionImmunological challengeHigh proliferative capacityCell cycleBulk RNA sequencing