2016
Predicting Outcomes on the Liver Transplant Waiting List in the United States
Hart A, Schladt DP, Zeglin J, Pyke J, Kim WR, Lake JR, Roberts JP, Hirose R, Mulligan DC, Kasiske BL, Snyder JJ, Israni AK. Predicting Outcomes on the Liver Transplant Waiting List in the United States. Transplantation 2016, 100: 2153-2159. PMID: 27490411, PMCID: PMC5369025, DOI: 10.1097/tp.0000000000001384.Peer-Reviewed Original ResearchConceptsDonation service areaLiver transplantWaiting listEnd-stage liver disease (MELD) scoreLiver transplant waiting listTransplant Recipients databaseLiver Disease scoreMELD exception pointsTransplant waiting listAvailability of organsTransplant probabilityRecipients databasePatient characteristicsScientific RegistryTransplant programsUS adultsDisease scorePredicting OutcomeException pointsTransplantBlood typeOutcomesOngoing disparitiesCorresponding percentilesOnline calculator
2012
A Consolidated Biovigilance System for Blood, Tissue and Organs: One Size Does Not Fit All
Pruett TL, Blumberg EA, Cohen DJ, Crippin JS, Freeman RB, Hanto DW, Mulligan DC, Green MD. A Consolidated Biovigilance System for Blood, Tissue and Organs: One Size Does Not Fit All. American Journal Of Transplantation 2012, 12: 1099-1101. PMID: 22487495, DOI: 10.1111/j.1600-6143.2011.03907.x.Peer-Reviewed Original ResearchConceptsOrgan transplant recipientsLimited organ availabilityPublic health servicesTransplant recipientsDonor testingOrgan availabilityWaiting listClinical practiceHealth servicesFormal recommendationsTransfer of organsDisease transmissionBloodOrgansOverall benefitTissueTransplantationSupport effortsRecipients
2010
Successful Transplantation of a Split Crossed Fused Ectopic Kidney into a Patient with End‐Stage Renal Disease
Mekeel KL, Daley SM, Andrews PE, Moss AA, Heilman RL, Mazur MJ, Chakkera HA, Hamawi K, Mulligan DC, Reddy K. Successful Transplantation of a Split Crossed Fused Ectopic Kidney into a Patient with End‐Stage Renal Disease. Journal Of Transplantation 2010, 2010: 383972. PMID: 20368777, PMCID: PMC2846343, DOI: 10.1155/2010/383972.Peer-Reviewed Original ResearchFused ectopic kidneyEctopic kidneySimultaneous kidney-pancreas transplantDeceased donor kidney transplantEnd-stage renal diseaseCongenital renal anomaliesKidney-pancreas transplantNormal renal functionDonor kidney transplantsPancreas transplantsKidney transplantRenal functionRenal diseaseParenchymal transectionRenal anomaliesSuccessful transplantationImmediate functionWaiting listTransplantPotential transplantsExcellent functionKidneyPotential donorsPatientsTransplantationNucleic Acid Testing (NAT) of Organ Donors: Is the ‘Best’ Test the Right Test? A Consensus Conference Report
Humar A, Morris M, Blumberg E, Freeman R, Preiksaitis J, Kiberd B, Schweitzer E, Ganz S, Caliendo A, Orlowski J, Wilson B, Kotton C, Michaels M, Kleinman S, Geier S, Murphy B, Green M, Levi M, Knoll G, Segev D, Brubaker S, Hasz R, Lebovitz D, Mulligan D, O’Connor K, Pruett T, Mozes M, Lee I, Delmonico F, Fischer S. Nucleic Acid Testing (NAT) of Organ Donors: Is the ‘Best’ Test the Right Test? A Consensus Conference Report. American Journal Of Transplantation 2010, 10: 889-899. PMID: 20121734, DOI: 10.1111/j.1600-6143.2009.02992.x.Peer-Reviewed Original ResearchConceptsNucleic acid testingOrgan donorsRisk factorsAcid testingInsufficient evidenceRoutine nucleic acid testingConsensus Conference reportDonor-derived infectionRisk of deathBehavioral risk factorsPotential organ donorsRisk of transmissionCandidate listingsHCV screeningDonor testingOrgan utilizationFalse-positive resultsOrgan offerProspective screeningDonor organsScreening modalityDonor lossWaiting listRapid turnaround timeTissue donors
2006
Reduced Priority MELD Score for Hepatocellular Carcinoma Does Not Adversely Impact Candidate Survival Awaiting Liver Transplantation
Sharma P, Harper AM, Hernandez JL, Heffron T, Mulligan DC, Wiesner RH, Balan V. Reduced Priority MELD Score for Hepatocellular Carcinoma Does Not Adversely Impact Candidate Survival Awaiting Liver Transplantation. American Journal Of Transplantation 2006, 6: 1957-1962. PMID: 16771808, DOI: 10.1111/j.1600-6143.2006.01411.x.Peer-Reviewed Original ResearchConceptsDeceased donor liver transplantationHepatocellular carcinomaHCC candidatesCandidate survivalLiver transplantationMELD scoreStage T1Waiting listEnd-stage liver diseaseDonor liver transplantationT2 hepatocellular carcinomaOrgan allocation policyUNOS databaseLiver transplantLiver diseasePatient survivalUnited NetworkHCC patientsIncidence rateOrgan SharingSurvivalTransplantationCarcinomaDropout rateTime period
2004
Liver transplantation for hepatocellular cancer: The impact of the MELD allocation policy
Wiesner RH, Freeman RB, Mulligan DC. Liver transplantation for hepatocellular cancer: The impact of the MELD allocation policy. Gastroenterology 2004, 127: s261-s267. PMID: 15508092, DOI: 10.1053/j.gastro.2004.09.040.Peer-Reviewed Original ResearchConceptsNumber of patientsHepatocellular cancerHCC patientsWaiting listLiver transplantationDeceased donorsExcellent long-term survivalPost-MELD eraAdvanced stage diseaseLiver transplant candidatesLong-term survivalHigh mortality rateProgression of HCCHCC recipientsPosttransplant survivalStage diseaseTransplant candidatesUnited NetworkDonor organsLower incidenceMortality ratePatientsAdvanced stageEarly assessmentTransplantationNew preservation solutions for use in liver transplantation
Mulligan D, Reddy K, Moss A. New preservation solutions for use in liver transplantation. Current Opinion In Organ Transplantation 2004, 9: 159-162. DOI: 10.1097/01.mot.0000127629.78517.06.Peer-Reviewed Original ResearchNew preservation solutionLiver transplantationPreservation solutionDonor liversClinical studiesEnd-stage liver diseasePartial liver graftsMainstay of treatmentOrgan preservation solutionsLiver graftsReperfusion injuryLiver diseaseMarginal organsWaiting listWisconsin solutionTransplantationExperimental modelContinuous perfusionIdentification of pathwaysLiverRecent findingsIschemiaNovel advancesCelsiorGraftLiver transplantation for hepatocellular carcinoma: The MELD impact
Sharma P, Balan V, Hernandez JL, Harper AM, Edwards EB, Rodriguez‐Luna H, Byrne T, Vargas HE, Mulligan D, Rakela J, Wiesner RH. Liver transplantation for hepatocellular carcinoma: The MELD impact. Liver Transplantation 2004, 10: 36-41. PMID: 14755775, DOI: 10.1002/lt.20012.Peer-Reviewed Original ResearchConceptsDeceased donor liver transplantationNew allocation policyHCC candidatesPerson yearsIncidence rateHepatocellular carcinomaLiver transplantationUNOS databaseEnd-stage liver diseaseT2 hepatocellular carcinomaDonor liver transplantationDropout rateDate of implementationHepatic decompensationNew MELDClinical deteriorationMELD scoreLiver diseaseStage T1United NetworkOrgan SharingWaiting listSurvivalTransplantationCarcinoma