2008
Chemotherapy With Bevacizumab Does Not Affect Liver Regeneration After Portal Vein Embolization in the Treatment of Colorectal Liver Metastases
Zorzi D, Chun YS, Madoff DC, Abdalla EK, Vauthey JN. Chemotherapy With Bevacizumab Does Not Affect Liver Regeneration After Portal Vein Embolization in the Treatment of Colorectal Liver Metastases. Annals Of Surgical Oncology 2008, 15: 2765. PMID: 18636296, PMCID: PMC5901734, DOI: 10.1245/s10434-008-0035-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic Combined Chemotherapy ProtocolsBevacizumabColorectal NeoplasmsEmbolization, TherapeuticFemaleFollow-Up StudiesHumansLiver NeoplasmsLiver RegenerationMaleMiddle AgedOrganoplatinum CompoundsOxaliplatinPortal VeinPrognosisProspective StudiesSurvival RateTreatment OutcomeConceptsPortal vein embolizationColorectal liver metastasesVascular endothelial growth factorLiver metastasesLiver regenerationPreoperative chemotherapyFLR hypertrophyLiver resectionVein embolizationFuture liver remnant volumeFLR volume increaseMajor liver resectionLiver remnant volumeEffect of chemotherapyImpairs liver regenerationEndothelial growth factorConclusionPreoperative chemotherapyConcurrent bevacizumabProspective databaseRight hepatectomyPostoperative outcomesConsecutive patientsRemnant volumeBevacizumabMurine model
2005
Portal Vein Embolization in Preparation for Major Hepatic Resection: Evolution of a New Standard of Care
Madoff DC, Abdalla EK, Vauthey JN. Portal Vein Embolization in Preparation for Major Hepatic Resection: Evolution of a New Standard of Care. Journal Of Vascular And Interventional Radiology 2005, 16: 779-790. PMID: 15947041, DOI: 10.1097/01.rvi.0000159543.28222.73.Peer-Reviewed Original ResearchConceptsPortal vein embolizationMajor hepatic resectionHepatic resectionVein embolizationFunctional hepatic reserveChronic liver diseasePortal blood flowNondiseased portionHospital stayHepatic reservePreoperative managementLiver diseaseLiver volumeBlood flowEmbolic agentResectionLiver regenerationMultidisciplinary approachEmbolizationPatientsLiverImaging techniquesComplex casesContraindicationsComplications