2022
An Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma
Madoff DC, Abi-Jaoudeh N, Braxton D, Goyal L, Jain D, Odisio BC, Salem R, Schattner M, Sheth R, Li D. An Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma. The Oncologist 2022, 27: 884-891. PMID: 35925597, PMCID: PMC9526481, DOI: 10.1093/oncolo/oyac139.Peer-Reviewed Original ResearchConceptsIntrahepatic cholangiocarcinomaBiomarker testingMultidisciplinary teamImage-guided liver biopsyMetastatic intrahepatic cholangiocarcinomaEvidence-based guidelinesIntrahepatic biliary treeNext-generation sequencingActionable genetic alterationsTreatment landscapeLiver biopsyMedical oncologistsInterventional oncologistsPoor prognosisAggressive malignancyBiliary treeTissue acquisitionBiopsy methodImaging modalitiesDesmoplastic natureGenetic alterationsTissue collectionNeedle choicePrecision medicineCholangiocarcinoma
2019
Transhepatic portal stent placement and jejunal varix embolization for management of treatment-limiting gastrointestinal bleeding in a patient with unresectable recurrent intrahepatic cholangiocarcinoma
Cornman-Homonoff J, Bassik N, Madoff DC. Transhepatic portal stent placement and jejunal varix embolization for management of treatment-limiting gastrointestinal bleeding in a patient with unresectable recurrent intrahepatic cholangiocarcinoma. Clinical Imaging 2019, 59: 188-191. PMID: 31837541, DOI: 10.1016/j.clinimag.2019.09.012.Peer-Reviewed Case Reports and Technical NotesConceptsRecurrent cholangiocarcinomaOnly potential cureRecurrent intrahepatic cholangiocarcinomaPoor patient outcomesUnresectable diseaseGastrointestinal bleedingChemotherapy administrationMyelosuppressive effectsTherapeutic mainstayDismal prognosisIntrahepatic cholangiocarcinomaVariceal embolizationStent placementPortal veinPatient outcomesPotential cureCholangiocarcinomaEmbolizationCytopeniasBleedingRegimenChemotherapyPatientsSurgeryPrognosis