Prognostic Significance of p16 and Its Relationship with Human Papillomavirus Status in Patients with Penile Squamous Cell Carcinoma: Results of 5 Years Follow-Up
Chahoud J, Zacharias N, Pham R, Qiao W, Guo M, Lu X, Alaniz A, Segarra L, Martinez-Ferrer M, Gleber-Netto F, Pickering C, Rao P, Pettaway C. Prognostic Significance of p16 and Its Relationship with Human Papillomavirus Status in Patients with Penile Squamous Cell Carcinoma: Results of 5 Years Follow-Up. Cancers 2022, 14: 6024. PMID: 36551510, PMCID: PMC9775956, DOI: 10.3390/cancers14246024.Peer-Reviewed Original ResearchPenile squamous cell carcinomaCancer-specific survivalSquamous cell carcinomaOverall survivalLymphovascular invasionCell carcinomaMedian cancer-specific survivalHigh-risk human papillomavirusHR-HPV statusMedian overall survivalTumor p16 statusHuman papillomavirus (HPV) statusHigh-risk HPVIndependent prognostic factorSingle-institution analysisClinico-pathologic variablesIHC staining patternSitu hybridization kitHR-HPVHPV statusPatient characteristicsPrognostic factorsSpecific survivalMultivariable analysisPrognostic significance