Arterial oxygen and carbon dioxide tension and acute brain injury in extracorporeal cardiopulmonary resuscitation patients: Analysis of the extracorporeal life support organization registry
Shou B, Ong C, Premraj L, Brown P, Tonna J, Dalton H, Kim B, Keller S, Whitman G, Cho S. Arterial oxygen and carbon dioxide tension and acute brain injury in extracorporeal cardiopulmonary resuscitation patients: Analysis of the extracorporeal life support organization registry. The Journal Of Heart And Lung Transplantation 2022, 42: 503-511. PMID: 36435686, PMCID: PMC10050131, DOI: 10.1016/j.healun.2022.10.019.Peer-Reviewed Original ResearchConceptsAcute brain injuryExtracorporeal Life Support Organization registrySevere hyperoxiaIschemic strokeIntracranial hemorrhageECPR patientsArterial oxygenBrain injuryLarge international multicenter cohortMultivariable logistic regression analysisExtracorporeal cardiopulmonary resuscitation patientsInternational multicenter cohortSignificant risk factorsBlood gas dataBlood gas parametersCardiopulmonary resuscitation patientsLogistic regression analysisCarbon dioxide tensionHospital mortalityMild hypercarbiaMulticenter cohortReperfusion injuryMultivariable analysisResuscitation patientsRisk factorsArterial Carbon Dioxide and Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation
Shou BL, Ong CS, Zhou AL, Al-Kawaz MN, Etchill E, Giuliano K, Dong J, Bush E, Kim BS, Choi CW, Whitman G, Cho SM. Arterial Carbon Dioxide and Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation. ASAIO Journal 2022, 68: 1501-1507. PMID: 35671442, PMCID: PMC9477972, DOI: 10.1097/mat.0000000000001699.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain InjuriesCarbon DioxideExtracorporeal Membrane OxygenationFemaleFemoral ArteryHumansIntracranial HemorrhagesMaleMiddle AgedRetrospective StudiesConceptsAcute brain injuryVenoarterial extracorporeal membrane oxygenationExtracorporeal membrane oxygenationPaCO 2Blood gas dataIntracranial hemorrhageBrain injuryMembrane oxygenationHypoxic-ischemic brain injuryArterial blood gas dataUnivariable logistic regression analysisArterial carbon dioxide tensionTertiary care centerVA-ECMO patientsArterial carbon dioxidePaCO 2 valuesLogistic regression analysisCarbon dioxide tensionPrevalence of ICHVA-ECMOAdult patientsCerebral edemaIschemic strokeCare centerBrain death