1991
Amelioration of renal ischemic injury by phosphocreatine
Rodriguez R, Stepke M, Maitz S, Cuono C, Sumpio B. Amelioration of renal ischemic injury by phosphocreatine. Journal Of Surgical Research 1991, 51: 271-274. PMID: 1921364, DOI: 10.1016/0022-4804(91)90106-v.Peer-Reviewed Original ResearchConceptsRenal ischemic injuryInitial ischemic insultPerfusion of kidneysKrebs-bicarbonate solutionMin of normothermicMM phosphocreatineRenal functionIschemic injuryKidney functionIschemic insultRenal arteryVivo ischemiaWarm ischemiaKrebs solutionKidneyPhosphocreatineAddition of phosphocreatineIschemiaSignificant improvementRegeneration of ATPGFRArteryNormothermicUreterInjury
1987
Comparison of effects of ATP-MgCl2 and adenosine-MgCl2 on renal function following ischemia
Sumpio BE, Hull MJ, Baue AE, Chaudry IH. Comparison of effects of ATP-MgCl2 and adenosine-MgCl2 on renal function following ischemia. American Journal Of Physiology 1987, 252: r388-r393. PMID: 3492930, DOI: 10.1152/ajpregu.1987.252.2.r388.Peer-Reviewed Original ResearchConceptsRenal functionATP-MgCl2Warm ischemiaATP-MgCl2 treatmentKrebs-HCO3 bufferMM ATP-MgCl2Comparison of effectsNormothermic ischemiaTransient improvementIschemiaSalutary effectsControl valuesUrine samplesFunctional parametersKidneyMajor breakdown productAdenosineTreatmentBreakdown productsMmHgPerfusateMinAdministration