Lamotrigine Emerging as a Driver of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: An 8-Year Retrospective Study
Glahn J, Almeida M, Kochen A, Noel O, Stogner V, Hsia H, Savetamal A. Lamotrigine Emerging as a Driver of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: An 8-Year Retrospective Study. Burns 2024, 50: 2114-2123. PMID: 39127578, DOI: 10.1016/j.burns.2024.07.006.Peer-Reviewed Original ResearchStevens-Johnson syndromeToxic epidermal necrolysisOff-label useEpidermal necrolysisCause of SJS/TENDiagnosis of SJS/TENBurn centerNon-bipolar mood disordersImpact clinical courseLength of stayBiopsy confirmationDesquamating rashRegional burn centerCausative drugsClinical coursePresenting symptomsClinical presentationSJS/TEN patientsPrescribed lamotriginePatient demographicsHospital courseRetrospective cohortStevens-JohnsonSevere manifestationsPatient population