On Monday, June 10, 2013, the State of Connecticut Stem Cell Research Advisory Committee had their grant review meeting.  Governor Dannel P. Malloy announced the awarding of $9.8 million in stem cell research funds to 23 Connecticut–based researchers. 

“Connecticut’s investment in stem cells continues to position the state on the cutting edge of biomedical research,” said Governor Malloy.  “These grants are critical to keeping and recruiting top scientists and help make possible innovative research that serves to improve people’s lives.”

The Connecticut Stem Cell Research Peer Review Committee reviewed 109 stem cell fund applications in accordance with National Institutes of Health guidelines and provided to the Advisory Committee its recommendations with respect to the scientific merits of each application.

Dr. Jewel Mullen, Department of Public Health Commissioner and Advisory Committee Chairperson, said “Connecticut’s stem cell program continues to fund some of the best basic and advanced stem cell research. This cutting-edge research holds great promise for clinical applications that will help address a number of significant health challenges.” 

The following grants were awarded to stem cell researchers at Yale:
Vascular Growth Factor Signaling in Human Neural Stem Cells
Jean-Leon Thomas, Department of Neurology

Hypoxia and Maintenance of Human Cancer Stem Cells
Zhong Yun, Department of Therapeutic Radiology

Testing the Oxidative Stress Theory of Ataxia-Telangiectasia Pathology Using Induced Pluripotent Stem Cells
Gerald Shadel, Department of Pathology

Characterize Nuclear Lamina-Associated Chromatin in Human ES Cells
Jie Yao, Department of Cell Biology

Elucidating the Role of Stem Cells in the Skin Tumor Pilomatricoma by In Vivo Imaging
Panteleimon Rompolas, Department of Genetics

Modeling Chronic Pain Condition with iPS Cells from Patients with “Man on Fire” Syndrome for Better Pharmaco-Genomic Analysis and Drug Testing
Stephen Waxman, Department of Neurology

The Role of Adipocyte Stem Cells in Lymphatic Vessel Differentiation
Nancy Ruddle, School of Public Health

Cell Therapy with ISL1+ Cardiac Progenitor Cells for Cardiac Repair After Myocardial Infarction
Oscar Bartulos, Department of Internal Medicine, Section of Cardiology

Potential of Human Pluripotent Stem Cell Derived Mesenchymal Cells for Lung Tissue Engineering
Sumati Sundaram, Department of Anesthesiology

Human ES-Derived Neuronal Cell Culture Systems for Investigating West Nile Virus Pathogenesis
Priti Kumar, Department of Internal Medicine, Section of Infectious Diseases

Pluripotency and Heterochromatin Topology
Tae Hoon Kim, Department of Genetics

Improving the Fidelity of Human iPSC with Epigenetic and Chemical Genetic Approaches
Andrew Xiao, Department of Genetics

Continued Service and Technology Development at the Yale Stem Cell Center Cores
Haifan Lin, Yale Stem Cell Center

For additional information, please visit www.ct.gov/dph/stemcell

This article was submitted by Liz Pantani on July 26, 2013.