Recent Pharmacology Theses
Here is a list of students who have recently defended their Ph.D. Thesis in Pharmacology, along with a brief description of their thesis work.
01/24/19 William Gray - Nucleoid Size Scaling and Intracellular Organization of Translation Across Bacteria.
01/14/19 Lee Ying - Epigentic Approaches to Understanding Adipogenesis, and Translational Approaches to Treating Obesity.
10/05/18 Molly Ryan - Understanding the Consequences of Oncogenic FGFR Mutations on Drug Resistance, Signaling, and Tumorigenesis
09/27/18 Daniel Iwamoto - Structural basis of the filamin A actin-binding domain interaction with F-actin
09/12/18 Lie Ma - Elucidation of the Activated State of Fibroblast Growth Factor Receptor
09/10/18 David E. Puleo -Targeting the Mutant JAK2 V617F Tyrosine Kinase by Small Molecules that Bind to its Pseudokinase Domain
03/01/18 Tomoaki Sasaki - Characterization of APOBEC3 Family Proteins as Potent DNA Mutators in Human Cancers
02/12/18 Elizabeth Mo - Augmentors are in vivo ligands to the ALK family of receptor tyrosine kinases: function and evolution
09/26/17 Chad Miller - Comprehensive Profiling of a Kinase Family Defines Features Essential for Selective Substrate Targeting
11/30/2016 Amelia Luciano - The Role of Akt1 & Clock S845 phosphorylation in Circadian Regulated Transcriptional Rhythms
09/23/2016 Allison Goldberg - An Exosite Required for Efficient Targeting of MAP Kinase Kinases by the Metalloproteinase Antrax Lethal Factor
08/12/2016 Yagmur Muftuoglu - Mechanisms of substrate specificity and insights into activation of phosphatidylionositol phosphate kinases
06/02/2016 Andrea Mislak - Insights into the Activity, Resistance, and Toxicity of Antivirals Targeting HIV Reverse Transcriptase
02/23/16 Phillip Murray - Discovery and Characterization of Ligands for the Receptor Tyrosine Kinase ALK: AUG-alpha, AUG-beta and Heparin
12/10/15 Yifei Yang - Molecular basis for Polycystin- 2 channel regulation and assembly its C-terminal tail
12/08/15 Jacqueline Heiss - Prion Protein Regulates Amyloid- Beta Dendritic Spine Pathology in a Mouse model if Alzheimer's Disease
10/15/15 Celeste Greer - Histone Deacetylases Positively Regulate Transcriptional Elongation
2/24/15 Oriana Fisher - Structural studies of Cerebral Cavernous Malformations 2 (CCM2) reveal the basis for its interactions with protein binding