Martin Schwartz, PhD
Biography
Research & Publications
News
Appointments
Biography
Martin Schwartz earned a BA in chemistry from New College in Sarasota FL and a PhD in physical chemistry from Stanford, where he worked in Harden McConnell’s lab on biophysics of phospholipid membranes.He then did postdoctoral research in biology at MIT in the laboratory of Richard Hynes where he studied interactions of fibronectin with cells and other proteins. He was on the faculty at Harvard Medical School, Scripps Research Institute and the University of Virginia prior to moving to Yale in 2011. Starting in the 1980’s, his lab was among the first to report that integrin mediated adhesion could regulate signaling pathways in cells;that integrin-mediated adhesion promotes cell survival, that integrins synergize with growth factor receptors to activate growth signaling pathways and that integrins regulate Rho family GTPases. His lab has also elucidated mechanotransduction pathways by which endothelial cells respond to fluid shear stress to activate inflammatory pathways linked to atherosclerosis. His current research program combines studies using biophysical, cellular and animal approaches to important questions about integrin signaling, mechanotransduction and disease in the vascular system.
Education & Training
- Postdoctoral fellowMIT (1982)
- PhDStanford University (1979)
- BANew College of the University South Florida (1975)
Honors & Recognition
Award | Awarding Organization | Date |
---|---|---|
Greenblatt Distinguished Lecture | Medical College of Georgia | 2021 |
Bolie Lecture | University of Colorado | 2019 |
Fellow of the American Society for Cell Biology | American Society for Cell Biology | 2017 |
Fellow of the American Association for Advancement of Science | American Association for Advancement of Science | 2016 |
Harold F. Dvorak Plenary Lecture | Harvard Medical School | 2013 |
Andrew P. Somlyo Honorary Lecture | Pennsylvania Muscle Institute, University of Pennsylvania | 2013 |
Robert W. Berliner Professor of Medicine | Yale School of Medicine | 2012 |
Hayashi Lecturer, Woods Hole MBL Physiology Course | Marine Biology Laboratory | 2009 |
James O. Davis Lectureship | University of Missouri | 2009 |
Professional Service
Organization | Role | Date |
---|---|---|
Gordon Research Conference, Signaling by Cell Adhesion Receptor | Chairperson | 2012 |
Frontiers in Cell Migration & Mechanotransduction | Chairperson | 2011 |
Gordon Research Conference, Vascular Cell Biology | Chairperson | 2011 |
Mechanotransduction in Physiology and Disease | Chairperson | 2009 |
ICI | Member ICI study section | 2008 - 2011 |
NAVBO | Member NAVBO Council | 2008 - 2010 |
Biochemical Journal (2006-2008) | Associate Editor | 2006 - 2015 |
Keystone conference on Signaling by Integrins and Growth Factor Receptors | Chairperson | 1998 |
Keystone conference on Integrins and Signaling Events in Cell Biology and Disease | Chairperson | 1996 |
CDF4 | Member CDF4 study section | 1996 - 2000 |
American Heart Association | Member vascular wall study section | 1993 - 1996 |
Matrix Biology (1997-2012) | Board Member | |
Journal of Cell Biology (2001-present) | Associate Editor | |
Journal of Cell Science (2006-present) | Board Member |
Departments & Organizations
- Cancer Signaling Networks
- Cardiovascular Medicine
- Cell Biology
- Cytoskeletal Dynamics
- Developmental Cell Biology and Genetics
- Diabetes Research Center
- Internal Medicine
- Leducq Transatlantic Network of Excellence
- Molecular Cell Biology, Genetics and Development
- Schwartz Lab
- Vascular Biology and Therapeutics Program
- Yale Cancer Center
- Yale Cardiovascular Research Center (YCVRC)
- Yale Combined Program in the Biological and Biomedical Sciences (BBS)