Tian-Min Chen
Laboratory Assistant 3
Research & Publications
Biography
News
Coauthors
Selected Publications
- APOBEC-1 deletion enhances cisplatin-induced acute kidney injuryGuo X, Blanc V, Davidson N, Velazquez H, Chen T, Moledina D, Moeckel G, Safirstein R, Desir G. APOBEC-1 deletion enhances cisplatin-induced acute kidney injury. Scientific Reports 2023, 13: 22255. PMID: 38097707, PMCID: PMC10721635, DOI: 10.1038/s41598-023-49575-3.
- mRNA Editing via the Apobec1 Gene Promotes Recovery from AKIGuo X, Velazquez H, Xu L, Cheng Z, Chen T, Tian Y, Bewersdorf J, Blanc V, Davidson N, Safirstein R, Desir G. mRNA Editing via the Apobec1 Gene Promotes Recovery from AKI. Journal Of The American Society Of Nephrology 2023, 34: 451-451. DOI: 10.1681/asn.20233411s1451b.
- Renalase Ameliorates AKI by Altering Mitochondrial Function to Induce Cellular Repair MechanismsGuo X, Chen R, Chen T, Safirstein R, Jonas E, Desir G. Renalase Ameliorates AKI by Altering Mitochondrial Function to Induce Cellular Repair Mechanisms. Journal Of The American Society Of Nephrology 2023, 34: 117-117. DOI: 10.1681/asn.20233411s1117b.
- Apobec-1 Limits Cisplatin and Ischemia-Reperfusion-Induced AKIGuo X, Xu L, Velazquez H, Chen T, Blanc V, Davidson N, Moeckel G, Safirstein R, Desir G. Apobec-1 Limits Cisplatin and Ischemia-Reperfusion-Induced AKI. Journal Of The American Society Of Nephrology 2022, 33: 359-360. DOI: 10.1681/asn.20223311s1359e.
- Renalase Protects Renal Injury by Maintaining Mitochondrial Dynamic HomeostasisGuo X, Chen R, Chen T, Moeckel G, Safirstein R, Jonas E, Desir G. Renalase Protects Renal Injury by Maintaining Mitochondrial Dynamic Homeostasis. Journal Of The American Society Of Nephrology 2022, 33: 359-359. DOI: 10.1681/asn.20223311s1359d.
- Inhibition of renalase drives tumour rejection by promoting T cell activationGuo X, Jessel S, Qu R, Kluger Y, Chen TM, Hollander L, Safirstein R, Nelson B, Cha C, Bosenberg M, Jilaveanu LB, Rimm D, Rothlin CV, Kluger HM, Desir GV. Inhibition of renalase drives tumour rejection by promoting T cell activation. European Journal Of Cancer 2022, 165: 81-96. PMID: 35219026, PMCID: PMC8940682, DOI: 10.1016/j.ejca.2022.01.002.
- Heightened Innate Immune Response to COVID-19 Infection in CKD: Implications to Poorer Outcome During CKDGuo X, Xu L, Chen T, Gorelick F, Desir G, Safirstein R. Heightened Innate Immune Response to COVID-19 Infection in CKD: Implications to Poorer Outcome During CKD. Journal Of The American Society Of Nephrology 2021, 32: 749-749. DOI: 10.1681/asn.20213210s1749c.
- Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinomaGao Y, Wang M, Guo X, Hu J, Chen TM, Finn S, Lacy J, Kunstman JW, H. C, Bellin MD, Robert ME, Desir GV, Gorelick FS. Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma. PLOS ONE 2021, 16: e0250539. PMID: 34587190, PMCID: PMC8480607, DOI: 10.1371/journal.pone.0250539.
- Kidney Targeted Renalase Agonist Peptide Rescues Severe Model of Cisplatin-Induced AKI and CKDGuo X, Xu L, Velazquez H, Chen T, Williams R, Heller D, Safirstein R, Desir G. Kidney Targeted Renalase Agonist Peptide Rescues Severe Model of Cisplatin-Induced AKI and CKD. Journal Of The American Society Of Nephrology 2020, 31: 230-230. DOI: 10.1681/asn.20203110s1230b.
- Apobec 1 Limits Cisplatin-Induced AKI by Regulating the Disposal of Pro-Ferroptotic LipidsGuo X, Velazquez H, Chen T, Blanc V, Davidson N, Safirstein R, Desir G. Apobec 1 Limits Cisplatin-Induced AKI by Regulating the Disposal of Pro-Ferroptotic Lipids. Journal Of The American Society Of Nephrology 2020, 31: 123-123. DOI: 10.1681/asn.20203110s1123d.
- Development of modified siRNA molecules incorporating 5-fluoro-2′-deoxyuridine residues to enhance cytotoxicityWu SY, Chen TM, Gmeiner WH, Chu E, Schmitz JC. Development of modified siRNA molecules incorporating 5-fluoro-2′-deoxyuridine residues to enhance cytotoxicity. Nucleic Acids Research 2013, 41: 4650-4659. PMID: 23449220, PMCID: PMC3632118, DOI: 10.1093/nar/gkt120.
- Translational autoregulation of thymidylate synthase and dihydrofolate reductase.Tai N, Schmitz JC, Liu J, Lin X, Bailly M, Chen TM, Chu E. Translational autoregulation of thymidylate synthase and dihydrofolate reductase. Frontiers In Bioscience-Landmark 2004, 9: 2521-6. PMID: 15353304, DOI: 10.2741/1413.
- Small Interfering Double-Stranded RNAs as Therapeutic Molecules to Restore Chemosensitivity to Thymidylate Synthase Inhibitor CompoundsSchmitz JC, Chen TM, Chu E. Small Interfering Double-Stranded RNAs as Therapeutic Molecules to Restore Chemosensitivity to Thymidylate Synthase Inhibitor Compounds. Cancer Research 2004, 64: 1431-1435. PMID: 14973067, DOI: 10.1158/0008-5472.can-03-1203.
- Translational Regulation as a Novel Mechanism for the Development of Cellular Drug ResistanceSchmitz J, Liu J, Lin X, Chen T, Yan W, Tai N, Gollerkeri A, Chu E. Translational Regulation as a Novel Mechanism for the Development of Cellular Drug Resistance. Cancer And Metastasis Reviews 2001, 20: 33-41. PMID: 11831645, DOI: 10.1023/a:1013100306315.