2024
An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk
Salama M, Tebben P, Nofal A. An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk. Journal Of Pediatric Endocrinology And Metabolism 2024, 37: 375-379. PMID: 38414167, DOI: 10.1515/jpem-2023-0494.Peer-Reviewed Case Reports and Technical NotesConceptsParathyroid hormoneCreatinine ratioUrine calcium-to-creatinine ratioHistory of biliary atresiaCalcium to creatinine ratioMonths prior to presentationAlmond milkCow's milk allergyMilk consumptionMonths of ageSevere hypercalcemiaBiliary atresiaAlternative to cow milkCow's milkD levelsLiver transplantationPlant-based milk alternativesCase reportInitial managementIntravenous fluidsMilk allergyHypercalcemiaMineral contentCalcium concentrationHypophosphatemia
2016
Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment
Tebben P, Singh R, Kumar R. Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment. Endocrine Reviews 2016, 37: 521-547. PMID: 27588937, PMCID: PMC5045493, DOI: 10.1210/er.2016-1070.Peer-Reviewed Original ResearchConceptsVitamin D receptorD receptorVitamin D-mediated hypercalcemiaElevated serum calcium concentrationsAssociated with elevated serumProduction of 1,25-dihydroxyvitamin DSuppressing PTH concentrationsAssociated with malignancyReduced bone densityRenal stone formersSerum calcium concentrationVitamin D metabolitesVitamin D<sub>3</sub>Primary hyperparathyroidismElevated serumPTH concentrationsMonoallelic mutationsClinical featuresCYP24A1 geneD metabolitesGranulomatous diseaseBiochemical diagnosisTumor cellsVitamin DHypercalcemia
2012
Vitamin D and the kidney
Kumar R, Tebben P, Thompson J. Vitamin D and the kidney. Archives Of Biochemistry And Biophysics 2012, 523: 77-86. PMID: 22426203, PMCID: PMC3361542, DOI: 10.1016/j.abb.2012.03.003.Peer-Reviewed Original Research
2005
Secreted frizzled-related protein-4 reduces sodium–phosphate co-transporter abundance and activity in proximal tubule cells
Berndt T, Bielesz B, Craig T, Tebben P, Bacic D, Wagner C, O’Brien S, Schiavi S, Biber J, Murer H, Kumar R. Secreted frizzled-related protein-4 reduces sodium–phosphate co-transporter abundance and activity in proximal tubule cells. Pflügers Archiv - European Journal Of Physiology 2005, 451: 579-587. PMID: 16151791, DOI: 10.1007/s00424-005-1495-2.ChaptersConceptsSecreted frizzled-related protein 4Na+-dependent Pi uptakeRenal Pi excretionOpossum kidneyProximal tubulesPi excretionFractional excretion of PiResponse to hypophosphatemiaFrizzled-related protein 4Excretion of PiEffect of secreted frizzled-related protein 4Proximal tubule cellsBrush border of the proximal tubuleCo-transportNa+-dependent Pi transportRenal brush border membraneRenal BBMVOK cellsTubule cellsRenal phosphateSurface expressionTransporter abundanceBrush border membraneProtein 4Infusion
1997
Three-Dimensional Computerized Reconstruction Illustration of Incremental Articular Cartilage Thinning
TEBBEN P, POPE T, HINSON G, BATNITZKY S, WETZEL L, DEPAOLIS D, MUNNS S, WILKINSON S, GORDON M. Three-Dimensional Computerized Reconstruction Illustration of Incremental Articular Cartilage Thinning. Investigative Radiology 1997, 32: 475-484. PMID: 9258736, DOI: 10.1097/00004424-199708000-00007.Peer-Reviewed Original ResearchConceptsThinning of articular cartilageArticular cartilageArticular cartilage thinningArticular cartilage reconstructionCartilage thinningVolume of cartilagePorcine knee modelIncrement thinningLimitations of measurement methodsShaved cartilageCartilage regionsCartilage reconstructionKnee modelThickness measurementsAverage errorAverage percent errorMeasurement methodThree-dimensionalAssessment of three-dimensionalDimensional measurementsTwo-dimensionalCartilageReconstructed imagesThicknessError