2024
High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine
Ottesen T, Wickersham J, Lawrence J, Antoniak S, Zezuilin O, Polonsky M, Antonyak S, Rozanova J, Dvoriak S, Pykalo I, Filippovych M, Altice F. High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine. PLOS ONE 2024, 19: e0305086. PMID: 39028735, PMCID: PMC11259278, DOI: 10.1371/journal.pone.0305086.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy prescriptionAntiretroviral therapyCD4 countSubstance use disordersIncreased levels of stigmaNational sampleLevel of stigmaIndependent of risk groupSuboptimal antiretroviral therapyInitiate antiretroviral therapyPopulation of peopleHIV expertsHIV incidenceHIV physiciansHIV treatmentKey populationsTransgender womenAntiretroviral treatmentFeeling thermometerDrinking alcoholSex workersPhysiciansSex partnersPWHRisk groups
2022
COVID-19 Vaccine Hesitancy and Associated Factors among People with HIV in the United States: Findings from a National Survey
Shrestha R, Meyer JP, Shenoi S, Khati A, Altice FL, Mistler C, Aoun-Barakat L, Virata M, Olivares M, Wickersham JA. COVID-19 Vaccine Hesitancy and Associated Factors among People with HIV in the United States: Findings from a National Survey. Vaccines 2022, 10: 424. PMID: 35335054, PMCID: PMC8949562, DOI: 10.3390/vaccines10030424.Peer-Reviewed Original ResearchCOVID-19 vaccine hesitancyVaccine hesitancySevere COVID-19 diseaseMean timeSample of PWHCells/mm3COVID-19 historyVaccine-related concernsGreater vaccine hesitancyCOVID-19 vaccineCOVID-19COVID-19 diseaseLower vaccine hesitancyCross-sectional online surveyCD4 countAssociated FactorsSide effectsHIVKey populationsPWHMultivariate linear regressionVaccineCOVID-19 epidemicHesitancyMost participants
2021
The Cooperative Re-Engagement Controlled trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes
Fanfair R, Khalil G, Williams T, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes. The Lancet Regional Health - Americas 2021, 3: 100057. PMID: 36777404, PMCID: PMC9903939, DOI: 10.1016/j.lana.2021.100057.Peer-Reviewed Original ResearchActive public health interventionMonths of randomizationViral load suppressionHIV viral loadPublic health interventionsViral loadCD4 countViral suppressionCare participantsCare strategiesHealth departmentsHealth interventionsDays of randomizationProportion of PWHStandard of careNon-Hispanic blacksHIV careContinuum outcomesHIV infectionMedian timeHIV transmissionCopies/Group overallClinic dataMedical care
2019
Self-reported antiretroviral therapy adherence and viral load in criminal justice-involved populations
Cunningham WE, Nance RM, Golin CE, Flynn P, Knight K, Beckwith CG, Kuo I, Spaulding A, Taxman FS, Altice F, Delaney JA, Crane HM, Springer SA. Self-reported antiretroviral therapy adherence and viral load in criminal justice-involved populations. BMC Infectious Diseases 2019, 19: 913. PMID: 31664910, PMCID: PMC6819597, DOI: 10.1186/s12879-019-4443-z.Peer-Reviewed Original ResearchConceptsViral loadART adherenceAdherence measuresSelf-reported antiretroviral therapy (ART) adherenceCriminal justice-involved populationsSelf-reported ART adherenceLogistic regressionSelf-reported health statusContinuum of HIVDetectable viral loadPlasma viral loadAIDS Research NetworkAntiretroviral therapy adherenceAssociation of adherenceHealth status levelsVisual analog scaleViral load dataMixed-effects logistic regressionMixed effects linear regressionEffects linear regressionJustice-involved populationsEffects logistic regressionVL outcomesCD4 countART doses
2018
The Impact of Housing and HIV Treatment on Health-Related Quality of Life Among People With HIV Experiencing Homelessness or Unstable Housing
Giordano TP, Gallagher K, Davich JAW, Rathore M, Borne D, Davies E, Altice FL, Cabral H. The Impact of Housing and HIV Treatment on Health-Related Quality of Life Among People With HIV Experiencing Homelessness or Unstable Housing. American Journal Of Public Health 2018, 108: s531-s538. PMID: 32941776, PMCID: PMC6290581, DOI: 10.2105/ajph.2018.304731.Peer-Reviewed Original ResearchPhysical component summary scoreComponent summary scoresHIV suppressionCD4 countHIV treatmentSummary scoresPatient-centred comprehensive careCD4 cell countProspective cohort studyMental component scoreHealth-related qualityQuality of lifeHousing statusMental health needsCohort studyHIV infectionClinical parametersComprehensive careHigh prevalenceCell countHealth needsUS sitesUnstable housingHigher PCSCubic millimeterAll-cause mortality among people with HIV released from an integrated system of jails and prisons in Connecticut, USA, 2007–14: a retrospective observational cohort study
Loeliger KB, Altice FL, Ciarleglio MM, Rich KM, Chandra DK, Gallagher C, Desai MM, Meyer JP. All-cause mortality among people with HIV released from an integrated system of jails and prisons in Connecticut, USA, 2007–14: a retrospective observational cohort study. The Lancet HIV 2018, 5: e617-e628. PMID: 30197101, PMCID: PMC6279524, DOI: 10.1016/s2352-3018(18)30175-9.Peer-Reviewed Original ResearchConceptsIndex releaseCause mortalityMortality rateRetrospective observational cohort studyCox proportional hazards modelLow CD4 countObservational cohort studyHIV surveillance dataCrude mortality rateGeneral US populationProportional hazards modelStandardised mortality ratiosSubstance use disordersSystems of careHIV/AIDSSurvival of peopleVirological failureAntiretroviral therapyCD4 countMedical comorbiditiesCohort studyRetrospective cohortMedian ageLiver diseaseViral load
2017
Integrated Tuberculosis/Human Immunodeficiency Virus Community-Based Case Finding in Rural South Africa: Implications for Tuberculosis Control Efforts
Shenoi SV, Moll AP, Brooks RP, Kyriakides T, Andrews L, Kompala T, Upadhya D, Altice FL, Eksteen FJ, Friedland G. Integrated Tuberculosis/Human Immunodeficiency Virus Community-Based Case Finding in Rural South Africa: Implications for Tuberculosis Control Efforts. Open Forum Infectious Diseases 2017, 4: ofx092. PMID: 28695145, PMCID: PMC5499582, DOI: 10.1093/ofid/ofx092.Peer-Reviewed Original ResearchHuman immunodeficiency virusIntensive case findingCase findingResistant TBTB casesHIV testingRural South AfricaOverall case notification rateConcurrent HIV testingHIV coinfection rateHIV-negative tuberculosisMedian CD4 countCD4 cell countHIV/TBDrug-resistant TBCase notification ratesCase-finding strategyHIV-positive individualsHigh-risk populationTB symptom screeningPopulation-level ratesCD4 countTuberculosis symptomsSymptom screeningTB elimination
2014
HIV Drug Therapy in the Americas 8–10 May 2014, Rio de Janeiro, Brazil
de Mesquita Fábio C, Pati P, de Barros Clarissa H, Juliana M, Taques D, Larissa D, de Freitas Marcelo A, Nestor S, Peter R, William P, Omar S, Andrew R, Dechao W, Peter R, Ard V, Raph H, Carl M, Robin W, Brian G, Julio M, Clifford L, Brendan L, Trevor H, Cal C, David W, Jose A, Keith H, Mark B, William T, Will G, Danielle P, Ivan W, Luis G, Valeska S, Waldo B, Federico A, Leandro K, Jorge S, Alberto L, Gabriela R, Jorge A, Marcelo L, Lynne M, Rosa B, Marinella D, Maria M, Margot K, Célia S, Letícia C, Ivete G, Laura F, Marcelo S, Marcelo G, Rosana F, Rohan H, Robert B, Isabel C, Jose V, Ivanka K, Antonella D, Fiona M, Anna S, He X, Woodie Z, Jean V, Marisol M, Andrew P, Jorge S, Luis S, Pedro C, Frederick A, Luis J, Felipe U, Patricia I, Veronica R, Yazmin M, Andrea G, Adriana V, Patricia U, Carlos M, Mark N, Juan S, Sobhie D, Anton P, Massimo G, Roy G, Daniel K, Brenda C, Yanink C, Sosa‐Rubi S, Ada K, Juan S, Raul O, Alondra L, Sergio B, David M, Luz P, Sobieszczyk M, Lake J, Clark J, Campos D, Veloso V, Moreira R, Cardoso S, Klausner J, Beatriz G, Robert P, Jesus C, Andrea G, Ubaldo R, Hamid V, Arantxa C, Víctor R, Gabriela H, Jeremy C, Alejandra C, Nitzia L, Claudia R, Steven D, Andrea G, Segundo L, Kelika K, Klausner J, Thomas C, Carlos C, Evaldo O, Letiano S, Roseane L, Luisa A, Jairo C, Leila S, Laine P, Lemos J, Oliveira‐Filho A, Vallinoto A, Carlos C, Ubaldo R, Andrea G, Oliveira‐Filho A, Suzy P, Marcelo P, Renata H, Eduardo A, MC Maradei‐Pereira L, Angelo C, Lemos J, Fernanda R, Marcelo W, Cortes C, Marcelo P, Lima D, Eduardo A, MC Maradei‐Pereira L, Lemos J, Oliveira‐Filho A, Steven D, Andrea G, Nathalie G, Maribel R, Susanna N, Mark S, Jacob L, Jeffrey F, Karam M, Margaret S, Annie L, David A, Anuj G, Liyun N, Evguenia S, William S, John M, Douglas D, Mariana K, Guillermo V, Javier T, Marcelo L, Robert P, Luis G, Alejandro F, Natalia G, Carlos T, Panagiotis C, Konstantina C, Eleni F, Panagiotis M, Ioannis M, Dimitra P, Drosos K, Georgios C, Carlos Y, Maribel A, Gabriela S, Condori E, Daniel S, Fanny C, Ada V, Soledad R, Irene F, Erica S, Silvina I, Alejandro H, Marcelo L, Patricia B, Lelia A, Marta F, Lisete D, Luiza N, Diana A, Rafael A, Hélder M, Luiza N, Lisete D, Lorena M, Rafael A, Hélder M, Trevor H, Rafael C, David W, Cal C, Joel G, Anthony M, Paul S, Andrew Z, Liu H, White K, Rhee M, Javier S, Nathan C, Jean‐Michel M, Keith H, Joe G, Rockstroh J, Edwin D, Xuelian W, White K, Fordyce M, Rhee M, Javier S, Vida R, Brenda C, Yanink C, Juan S, Victor R, Hamid V, Gabriela H, Jeremy C, Anita S, Robertino M, Leslie N, David M, Keith R, Rima K, Abram M, Rhee M, Fordyce M, Javier S, Miller M, White K, Rodrigo P, Clara F, Paula L, Cerdeira S, Busch M, Saeed S, Silvia K, Emiliano B, Natalia A, Gonzalo C, Gabriela B, De Leon J, Analia C, Gladys A, Cristina G, Pierina D, Marwan A, Moraima M, Martin C, Marbelys H, Mario C, Yajaira R, Anselmo R, Graciela L, Leopoldo D, Miguel M, Rafael N, Maricruz R, Cristina G, Gladys A, Pierina D, Marbelys H, Héctor R, Domingo G, Flor P, Rafael N, Eugenia P, Alejandra M, Camila M, Fernanda N, Andres G, Carlos G, Edwin D, Jason F, Anton P, Antonio A, Pere D, Will G, Thai N, David S, Doug C, Jose A, Joseph G, Ramin E, L W, Thai N, Emiliano B, Cynthia B, Carlos F. HIV Drug Therapy in the Americas 8–10 May 2014, Rio de Janeiro, Brazil. Journal Of The International AIDS Society 2014, 17: 19180. PMID: 24815847, PMCID: PMC4015307, DOI: 10.7448/ias.17.2.19180.Peer-Reviewed Original ResearchConceptsHIV/AIDS epidemicAIDS epidemicHIV health care servicesCurrent HIV/AIDS epidemicNotifiable Diseases Information SystemViral load suppressionMortality Information SystemHealth care servicesHIV/AIDSCD4 countVL suppressionHIV transmissionCare servicesEpidemicTreatmentSuppressionSocial disparitiesHIVRegional differencesAIDS
2012
Early Identification of HIV: Empirical Support for Jail-Based Screening
de Voux A, Spaulding AC, Beckwith C, Avery A, Williams C, Messina LC, Ball S, Altice FL. Early Identification of HIV: Empirical Support for Jail-Based Screening. PLOS ONE 2012, 7: e37603. PMID: 22662177, PMCID: PMC3360747, DOI: 10.1371/journal.pone.0037603.Peer-Reviewed Original ResearchConceptsAntiretroviral treatmentClient-level dataCD4 countHIV testingMedian CD4 countRoutine HIV testingInitial CD4 countTime of diagnosisInjection drug useYounger median ageUnprotected anal intercourseCross-sectional analysisAntiretroviral therapyMedian agePharmacy costsDisease progressionAnal intercoursePost dischargeSubset of individualsNew diagnosisDrug useEarly identificationDiagnosisCells/Baseline data
2010
A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization
Azar MM, Springer SA, Meyer JP, Altice FL. A systematic review of the impact of alcohol use disorders on HIV treatment outcomes, adherence to antiretroviral therapy and health care utilization. Drug And Alcohol Dependence 2010, 112: 178-193. PMID: 20705402, PMCID: PMC2997193, DOI: 10.1016/j.drugalcdep.2010.06.014.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHealth care utilizationHIV treatment outcomesAlcohol use disorderPoor HIV treatment outcomesCare utilizationTreatment outcomesAntiretroviral therapyUse disordersImpact of AUDHealth service utilizationHIV/AIDSCD4 countHIV statusMedication adherenceService utilizationDATA SYNTHESISAnimal studiesElectronic databasesSystematic reviewAlcohol useTherapyPrimary articlesGoogle ScholarAdherenceOutcomesImproved HIV and Substance Abuse Treatment Outcomes for Released HIV-Infected Prisoners: The Impact of Buprenorphine Treatment
Springer SA, Chen S, Altice FL. Improved HIV and Substance Abuse Treatment Outcomes for Released HIV-Infected Prisoners: The Impact of Buprenorphine Treatment. Journal Of Urban Health 2010, 87: 592-602. PMID: 20177974, PMCID: PMC2900572, DOI: 10.1007/s11524-010-9438-4.Peer-Reviewed Original ResearchConceptsOpioid agonist therapySubstance abuse treatment outcomesTreatment outcomesNon-detectable viral loadOpioid treatment outcomesBuprenorphine/naloxoneDSM-IV criteriaAgonist therapyAntiretroviral therapyCD4 countOpioid cravingAdverse eventsBuprenorphine treatmentOpioid dependenceViral loadUrine testingHIVTherapyVulnerable populationsWeeksOutcomesNLXTrialsInductionLikert scale
2009
Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy
Springer SA, Chen S, Altice F. Depression and symptomatic response among HIV-infected drug users enrolled in a randomized controlled trial of directly administered antiretroviral therapy. AIDS Care 2009, 21: 976-983. PMID: 20024753, PMCID: PMC2797133, DOI: 10.1080/09540120802657555.Peer-Reviewed Original ResearchConceptsInjection drug usersCES-D scoresMajor depressive disorderAntiretroviral therapyCD4 countDepressive symptomsDrug usersDrug useHIV-1 RNA levelsProspective clinical trialsSubstance abuse treatment servicesSelf-administered therapyActive drug useNon-Caucasian raceSix-month followSix-month dataAntidepressant medicationAntiretroviral treatmentPoor adherenceSymptomatic responseMale genderClinical trialsDepressive disorderDepression ScaleDrug treatmentEarly initiation of antiretroviral therapy results in decreased morbidity and mortality among patients with TB and HIV
Tabarsi P, Saber‐Tehrani A, Baghaei P, Padyab M, Mansouri D, Amiri M, Masjedi MR, Altice FL. Early initiation of antiretroviral therapy results in decreased morbidity and mortality among patients with TB and HIV. Journal Of The International AIDS Society 2009, 12: 14-14. PMID: 19607726, PMCID: PMC2734561, DOI: 10.1186/1758-2652-12-14.Peer-Reviewed Original ResearchCells/mm3HIV/TB patientsCD4 countTB patientsTB treatmentGroup IAntiretroviral therapyEarly initiationGroup IIAntiretroviral therapy resultsHIV-infected patientsNew opportunistic infectionsActive antiretroviral therapyMasih Daneshvari HospitalRetrospective chart reviewAdverse drug reactionsInjection of drugsDrug-drug interactionsComplications of managementDrug toxicity profilesAdvanced HIVChart reviewImproved survivalRetrospective reviewOpportunistic infections
2007
Improving the Care for HIV-Infected Prisoners: An Integrated Prison-Release Health Model
Springer S, Altice F. Improving the Care for HIV-Infected Prisoners: An Integrated Prison-Release Health Model. 2007, 535-555. DOI: 10.1007/978-0-387-71695-4_30.Peer-Reviewed Original ResearchAntiretroviral therapyHIV careViral loadHIV-1 RNA levelsCommunity settingsActive antiretroviral therapyComorbid medical conditionsHuman Services guidelinesNormal life expectancySerious psychiatric illnessSubstance use disordersHIV/AIDSDepartment of HealthHAART regimensCD4 countHIV diseaseHIV infectionChronic conditionsPsychiatric illnessMedical conditionsGeneral populationHealth care institutionsUse disordersHIVViral replication