2015
Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25–35-treated differentiated PC12 cells
Xu P, Wang H, Li Z, Yang Z. Triptolide attenuated injury via inhibiting oxidative stress in Amyloid-Beta25–35-treated differentiated PC12 cells. Life Sciences 2015, 145: 19-26. PMID: 26679104, DOI: 10.1016/j.lfs.2015.12.018.Peer-Reviewed Original ResearchConceptsDifferentiated PC12 cellsAβ25-35Alzheimer's diseaseOxidative stressPC12 cellsAβ25-35-induced apoptosisTreatment of ADReactive oxygen speciesPotential neuroprotective effectsEffects of triptolideAβ25-35-induced cytotoxicityDecreased oxidative stressSuperoxide dismutaseProtective functionNeuroprotective effectsImmunohistochemical stainingProtective effectResults of MTTAmyloid betaHerb TripterygiumNervous systemAbnormal depositionCytometry assaysWestern blotTriptolide
2013
Neuroprotective Effect of Leukemia Inhibitory Factor on Antimycin A-Induced Oxidative Injury in Differentiated PC12 Cells
Han Y, Xu J, Li Z, Yang Z. Neuroprotective Effect of Leukemia Inhibitory Factor on Antimycin A-Induced Oxidative Injury in Differentiated PC12 Cells. Journal Of Molecular Neuroscience 2013, 50: 577-585. PMID: 23636893, DOI: 10.1007/s12031-013-0004-x.Peer-Reviewed Original ResearchConceptsLeukemia inhibitory factorOxidative injuryNeuroprotective effectsPC12 cellsInhibitory factorOxidative stressExerts neuroprotective effectsSuperoxide dismutase levelsElevated reactive oxygen species (ROS) levelsPC12 cell viabilityReactive oxygen species levelsHoechst 33342 stainingNeuron injuryDifferentiated PC12 cellsDiphenyltetrazolium bromide assayNeuroendocrine effectsNeurotrophic cytokinesPresence of LIFOxygen species levelsDismutase levelsInjuryAntioxidative effectsBromide assayDimethylthiazol-2Cell viability