2016
Nano-TiO2 induces autophagy to protect against cell death through antioxidative mechanism in podocytes
Zhang X, Yin H, Li Z, Zhang T, Yang Z. Nano-TiO2 induces autophagy to protect against cell death through antioxidative mechanism in podocytes. Cell Biology And Toxicology 2016, 32: 513-527. PMID: 27430495, DOI: 10.1007/s10565-016-9352-y.Peer-Reviewed Original ResearchmiR-200 family promotes podocyte differentiation through repression of RSAD2
Li Z, Yin H, Hao S, Wang L, Gao J, Tan X, Yang Z. miR-200 family promotes podocyte differentiation through repression of RSAD2. Scientific Reports 2016, 6: 27105. PMID: 27251424, PMCID: PMC4890021, DOI: 10.1038/srep27105.Peer-Reviewed Original ResearchConceptsMiR-200 familyPodocyte differentiationKidney developmentCell differentiationMiR-200aDifferentiation of podocytesUnderlying molecular mechanismsCellular functionsRNA interferencePostnatal mouse kidneyMolecular mechanismsDifferentiated cellsNovel roleMature podocytesHigher upregulationProtein 2 expressionRSAD2MiR-200bMiR-429DifferentiationPodocyte dedifferentiationRepressionCharacteristic phenotypic featuresPhenotypic featuresMorphological characteristics
2011
Oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in C6 cells
Xu J, Xu P, Li Z, Huang J, Yang Z. Oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in C6 cells. Journal Of Biomedical Materials Research Part A 2011, 100A: 738-745. PMID: 22213249, DOI: 10.1002/jbm.a.33270.Peer-Reviewed Original ResearchConceptsC6 cell apoptosisC6 cellsCell apoptosisReactive oxygen speciesAnti-tumor effectsAnti-glioma treatmentHoechst 33342 stainingTime-dependent mannerC6 cell deathFlow cytometricTotal SODGlioma cellsOxidative stressIntracellular accumulationDimethylthiazol-2Human cancersDiphenyltetrazolium bromideApoptosisCell deathEffect of HACellular levelOxygen speciesCellsCancer