The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil
Xu J, Xu P, Li Z, Xiao L, Yang Z. The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil. Cellular & Molecular Biology Letters 2013, 18: 494-506. PMID: 23990403, PMCID: PMC6275801, DOI: 10.2478/s11658-013-0102-3.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidAnimalsApoptosisCell Line, TumorGliomaGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaHumansPiperidinesRatsRemifentanilThiadiazolesConceptsGlycogen synthase kinase-3βSynthase kinase-3βGSK-3β activationC6 cell apoptosisCell apoptosisHoechst 33342 stainingGSK-3βKinase-3βSelective small molecule inhibitorsSmall molecule inhibitorsGlioma cell apoptosisFlow cytometryCell deathReceptor signalingMolecule inhibitorsTime-dependent mannerNMDA receptor signalingTumor cell apoptosisTumor cell proliferationCellular levelCell proliferationApoptosisC6 cell deathN-methyl-D-aspartate receptorsCell viability