2016
miR-200 family promotes podocyte differentiation through repression of RSAD2
Li Z, Yin H, Hao S, Wang L, Gao J, Tan X, Yang Z. miR-200 family promotes podocyte differentiation through repression of RSAD2. Scientific Reports 2016, 6: 27105. PMID: 27251424, PMCID: PMC4890021, DOI: 10.1038/srep27105.Peer-Reviewed Original ResearchConceptsMiR-200 familyPodocyte differentiationKidney developmentCell differentiationMiR-200aDifferentiation of podocytesUnderlying molecular mechanismsCellular functionsRNA interferencePostnatal mouse kidneyMolecular mechanismsDifferentiated cellsNovel roleMature podocytesHigher upregulationProtein 2 expressionRSAD2MiR-200bMiR-429DifferentiationPodocyte dedifferentiationRepressionCharacteristic phenotypic featuresPhenotypic featuresMorphological characteristics
2014
MiRNA expression profile and miRNA–mRNA integrated analysis (MMIA) during podocyte differentiation
Li Z, Wang L, Xu J, Yang Z. MiRNA expression profile and miRNA–mRNA integrated analysis (MMIA) during podocyte differentiation. Molecular Genetics And Genomics 2014, 290: 863-875. PMID: 25433550, DOI: 10.1007/s00438-014-0960-z.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell LineDown-RegulationGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksGenes, ReporterHEK293 CellsHumansMiceMicroRNAsOligonucleotide Array Sequence AnalysisPodocytesPromoter Regions, GeneticReal-Time Polymerase Chain ReactionRNA, MessengerUp-RegulationConceptsPodocyte differentiationMiRNA-mRNAAbnormal miRNAsMiRNA-target pairsMiRNA expression profilesMouse podocyte cell lineDual-luciferase reporterPodocyte cell lineGene OntologyPotential new moleculesExpression trendsUndifferentiated podocytesExpression profilesPathway analysisQuantitative real-time polymerase chain reactionPotential crosstalkMiRNA expressionLuciferase reporterMicroarray dataMiRNAsCell typesMRNA microarrayProminent cell typeMiRNAEssential role