2014
MiRNA expression profile and miRNA–mRNA integrated analysis (MMIA) during podocyte differentiation
Li Z, Wang L, Xu J, Yang Z. MiRNA expression profile and miRNA–mRNA integrated analysis (MMIA) during podocyte differentiation. Molecular Genetics And Genomics 2014, 290: 863-875. PMID: 25433550, DOI: 10.1007/s00438-014-0960-z.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell LineDown-RegulationGene Expression ProfilingGene Expression RegulationGene Regulatory NetworksGenes, ReporterHEK293 CellsHumansMiceMicroRNAsOligonucleotide Array Sequence AnalysisPodocytesPromoter Regions, GeneticReal-Time Polymerase Chain ReactionRNA, MessengerUp-RegulationConceptsPodocyte differentiationMiRNA-mRNAAbnormal miRNAsMiRNA-target pairsMiRNA expression profilesMouse podocyte cell lineDual-luciferase reporterPodocyte cell lineGene OntologyPotential new moleculesExpression trendsUndifferentiated podocytesExpression profilesPathway analysisQuantitative real-time polymerase chain reactionPotential crosstalkMiRNA expressionLuciferase reporterMicroarray dataMiRNAsCell typesMRNA microarrayProminent cell typeMiRNAEssential role
2013
Developmental changes of BKCa channels depend on differentiation status in cultured podocytes
Yang J, Xu P, Xie Y, Li Z, Xu J, Zhang T, Yang Z. Developmental changes of BKCa channels depend on differentiation status in cultured podocytes. In Vitro Cellular & Developmental Biology - Animal 2013, 49: 205-211. PMID: 23443253, DOI: 10.1007/s11626-013-9590-8.Peer-Reviewed Original ResearchConceptsBKCa channelsWhole-cell patch-clamp techniqueChannel protein expressionIon channel expressionDevelopmental changesPatch-clamp techniqueLarge-conductance Ca2Development of kidneyRemarkable cell typeImmortalized mouse podocyte cell lineImportant ion channelsMouse podocyte cell linePodocyte cell lineChannel expressionFunctional maturationCell signalingCultured podocytesKidney developmentKidney glomeruliProtein expressionPodocytesCell typesDifferentiation statusIon channelsCell lines