2013
Neuroprotective Effect of Leukemia Inhibitory Factor on Antimycin A-Induced Oxidative Injury in Differentiated PC12 Cells
Han Y, Xu J, Li Z, Yang Z. Neuroprotective Effect of Leukemia Inhibitory Factor on Antimycin A-Induced Oxidative Injury in Differentiated PC12 Cells. Journal Of Molecular Neuroscience 2013, 50: 577-585. PMID: 23636893, DOI: 10.1007/s12031-013-0004-x.Peer-Reviewed Original ResearchConceptsLeukemia inhibitory factorOxidative injuryNeuroprotective effectsPC12 cellsInhibitory factorOxidative stressExerts neuroprotective effectsSuperoxide dismutase levelsElevated reactive oxygen species (ROS) levelsPC12 cell viabilityReactive oxygen species levelsHoechst 33342 stainingNeuron injuryDifferentiated PC12 cellsDiphenyltetrazolium bromide assayNeuroendocrine effectsNeurotrophic cytokinesPresence of LIFOxygen species levelsDismutase levelsInjuryAntioxidative effectsBromide assayDimethylthiazol-2Cell viability
2012
Protective effects of leukemia inhibitory factor against oxidative stress during high glucose-induced apoptosis in podocytes
Xu J, Li Z, Xu P, Yang Z. Protective effects of leukemia inhibitory factor against oxidative stress during high glucose-induced apoptosis in podocytes. Cell Stress And Chaperones 2012, 17: 485-493. PMID: 22270613, PMCID: PMC3368028, DOI: 10.1007/s12192-012-0325-7.Peer-Reviewed Original ResearchConceptsHigh glucose-induced apoptosisLeukemia inhibitory factorGlucose-induced apoptosisOxidative stressInhibitory factorEffects of LIFNicotinamide adenine dinucleotide phosphate (NADPH) oxidaseHigh glucose-induced oxidative stressGlucose-induced oxidative stressElevated levelsAdenine Dinucleotide Phosphate OxidaseHigh glucose-induced cytotoxicityReactive oxygen speciesAnti-inflammatory stimuliLevels of SODDiabetic nephropathyDiphenyltetrazolium bromide assayInterleukin-6 familyCaspase-3 activityTubular regenerationProtective effectPotential therapyPleiotropic glycoproteinFlow cytometryFlow cytometric