Illustration of temporal evolution in patients with metastatic renal cell carcinoma (mRCC) using both circulating tumor DNA (ctDNA) and tissue-based genomic data.
Zengin Z, Weipert C, Hsu J, Salgia N, Hensel C, Maughan B, Rathi N, Goel D, Agarwal N, Choueiri T, Pal S. Illustration of temporal evolution in patients with metastatic renal cell carcinoma (mRCC) using both circulating tumor DNA (ctDNA) and tissue-based genomic data. Journal Of Clinical Oncology 2021, 39: 347-347. DOI: 10.1200/jco.2021.39.6_suppl.347.Peer-Reviewed Original ResearchMetastatic renal cell carcinomaGenomic profilingCtDNA alterationsMost common histologySubset of ptsRenal cell carcinomaSeparate validation cohortTissue-based assessmentProportion of alterationsCommon histologyMedian timeValidation cohortCell carcinomaCtDNA assessmentClear cellsCtDNA analysisTumor DNACohortGene panelTissue samplesTissue assessmentMonthsOnly alterationSignificant differencesPatients