Squalene Biosynthesis in Engineered Escherichia Coli
Zhang W, Li Y, Xie L, Hu Y. Squalene Biosynthesis in Engineered Escherichia Coli. Pharmaceutical Fronts 2023, 05: e321-e329. DOI: 10.1055/s-0043-1776291.Peer-Reviewed Original ResearchMevalonate pathwaySqualene productionProduction of squaleneEngineered Escherichia coliSqualene synthasesChassis cellsMVA pathwayDimethylallyl diphosphateEscherichia coli strainsExpression strengthMetabolic fluxExtinct animalsXL1-BlueDifferent speciesSqualene biosynthesisEscherichia coliColi strainsGenesPathwayNatural triterpenoidIspH