2022
Cellular diversity and gene expression profiles in the male and female brain of Aedes aegypti
Cui Y, Behura SK, Franz AWE. Cellular diversity and gene expression profiles in the male and female brain of Aedes aegypti. BMC Genomics 2022, 23: 119. PMID: 35144549, PMCID: PMC8832747, DOI: 10.1186/s12864-022-08327-9.Peer-Reviewed Original ResearchMeSH KeywordsAedesAnimalsBrainDengue VirusFemaleHumansMaleMosquito VectorsTranscriptomeZika VirusZika Virus InfectionConceptsFemale brainMedulla neuronsCell clustersDimorphic behaviorsCell typesBrain cell typesSingle-nucleus RNA sequencingMonoaminergic neuronsProjection neuronsMosquito brainMale brainNeuronsKenyon cellsBrainYellow feverCell atlasCellular compositionGene expression profilesFemale mosquitoesGliaMosquito vectorsType compositionType proportionsRNA sequencingAdult males
2019
Zika Virus Dissemination from the Midgut of Aedes aegypti is Facilitated by Bloodmeal-Mediated Structural Modification of the Midgut Basal Lamina
Cui Y, Grant DG, Lin J, Yu X, Franz AWE. Zika Virus Dissemination from the Midgut of Aedes aegypti is Facilitated by Bloodmeal-Mediated Structural Modification of the Midgut Basal Lamina. Viruses 2019, 11: 1056. PMID: 31739432, PMCID: PMC6893695, DOI: 10.3390/v11111056.Peer-Reviewed Original ResearchConceptsZika virusMidgut basal laminaBasal laminaDengue 4 virusDissemination patternsSame mosquito speciesMeal ingestionZIKV infectionZIKV disseminationInfectious bloodmealHuman pathogenic virusesChikungunya virusInfected mosquitoesViral titersVirus disseminationMosquito midgutSalivary glandsFive daysBloodmeal digestionBloodmeal ingestionIngestionVirusMidgut infectionIncreased numberKey tissues