Myricetin suppresses differentiation of 3 T3-L1 preadipocytes and enhances lipolysis in adipocytes
Wang Q, Wang S, Yang X, You P, Zhang W. Myricetin suppresses differentiation of 3 T3-L1 preadipocytes and enhances lipolysis in adipocytes. Nutrition Research 2015, 35: 317-327. PMID: 25724338, DOI: 10.1016/j.nutres.2014.12.009.Peer-Reviewed Original ResearchMeSH Keywords3T3-L1 CellsAdipocytesAdipogenesisAnimalsAnti-Obesity AgentsCarrier ProteinsCCAAT-Enhancer-Binding Protein-betaCCAAT-Enhancer-Binding ProteinsCell DifferentiationCell SurvivalDown-RegulationFlavonoidsLipaseLipid MetabolismLipolysisLipoprotein LipaseMiceMitogen-Activated Protein KinasesPerilipin-1PhosphoproteinsPhosphorylationPPAR gammaRNA, MessengerSignal TransductionSterol EsteraseTriglyceridesConceptsJun N-terminal kinaseExtracellular signal-regulated kinaseT3-L1 preadipocytesN-terminal kinaseSignal-regulated kinaseTranscription factorsAdipogenesis-related transcription factorsT3-L1T3-L1 adipocytesAdipogenic transcription factorsGlucose transporter 4Phosphorylation of extracellular signal-regulated kinasePhosphorylation levels of extracellular signal-regulated kinaseDifferentiation of preadipocytesAdipocyte protein 2Levels of extracellular signal-regulated kinasePerilipin APeroxisome proliferator-activated receptor gAdipocyte differentiationDose-dependent increaseTransporter 4Adipocyte lipolysisPhosphorylation levelsProtein AMYR treatment