2004
Home continuous positive inotropic infusion as a bridge to cardiac transplantation in patients with end-stage heart failure
Upadya S, Lee FA, Saldarriaga C, Verma S, Sedrakyan A, Nystrom K, Katz SD. Home continuous positive inotropic infusion as a bridge to cardiac transplantation in patients with end-stage heart failure. The Journal Of Heart And Lung Transplantation 2004, 23: 466-472. PMID: 15063407, DOI: 10.1016/s1053-2498(03)00203-1.Peer-Reviewed Original ResearchConceptsPositive inotropic therapyInotropic therapyCardiac transplantationFunctional capacityDecreased health care costsEnd-stage heart failureImplantable cardioverter-defibrillator dischargeHome therapy patientsStatus 1B patientsInitiation of therapyStable clinical statusNumber of hospitalizationsPre-treatment baselineImplantable cardioverter defibrillatorHealth care costsActuarial survivalInotropic treatmentRenal functionConsecutive patientsHeart failureClinical statusHemodynamic monitoringHome infusionInotropic infusionUnited Network
1995
Medical Therapy and Prognosis in Chronic Heart Failure Lessons from Clinical Trials
Ramahi T, Lee F. Medical Therapy and Prognosis in Chronic Heart Failure Lessons from Clinical Trials. Cardiology Clinics 1995, 13: 5-26. PMID: 7796432, DOI: 10.1016/s0733-8651(18)30058-4.Peer-Reviewed Original ResearchConceptsChronic heart failureLeft ventricular dysfunctionIntermediate-term improvementVentricular dysfunctionClinical trialsHeart failureLong-term improvementHemodynamic improvementLong-term effectsFunctional capacityShort-term hemodynamic improvementSystolic left ventricular dysfunctionChronic left ventricular dysfunctionACE inhibitor therapyRole of diureticsImmediate symptomatic reliefMajor clinical trialsSympathetic nervous systemMarker of prognosisGoal of therapyPure vasodilationAldosterone systemDirect vasodilatorAcute stabilizationPharmacologic therapy