2021
Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association
Kernan WN, Viera AJ, Billinger SA, Bravata DM, Stark SL, Kasner SE, Kuritzky L, Towfighi A, Arteriosclerosis T. Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke 2021, 52: e558-e571. PMID: 34261351, DOI: 10.1161/str.0000000000000382.Peer-Reviewed Original ResearchConceptsRecurrent strokePoststroke carePrimary careAmerican Heart Association/American Stroke AssociationOngoing functional impairmentPatient-centered primary careAmerican Stroke AssociationHigh blood pressureEvidence-based carePrimary care practicesPrimary care teamsPatient-centered careQuality of lifePoststroke managementLifestyle modificationAdult patientsLate complicationsQuality improvement strategiesBlood pressureAtrial fibrillationCarotid stenosisStroke AssociationOngoing careRisk factorsCare team
2011
Boosting enrolment in clinical trials: validation of a regional network model
Kernan W, Viscoli C, Brass L, Amatangelo M, Birch A, Clark W, Conwit R, Furie K, Gorman M, Pesapane B, Kleindorfer D, Lovejoy A, Osborne J, Silliman S, Zweifler R, Horwitz R. Boosting enrolment in clinical trials: validation of a regional network model. Clinical Trials 2011, 8: 645-653. PMID: 21824978, PMCID: PMC3852692, DOI: 10.1177/1740774511414925.Peer-Reviewed Original ResearchConceptsClinical trialsTransient ischemic attackNames of patientsEligible patientsIschemic attackStroke preventionDrug adherenceStroke therapyActive surveillanceAverage monthly rateHome visitsPatientsHospitalTrial researchParticipant costsOutreach NetworkMultiple hospitalsTrialsStudy intervalNational InstituteEnrollmentMonthly rateStrokeParticipantsReproducible methodAlmost Internists: Analysis of Students Who Considered Internal Medicine but Chose Other Fields
Durning SJ, Elnicki DM, Cruess DF, Reddy S, Kernan WN, Harrell HE, Schwartz MD, Fagan MJ, Battistone M, Hauer KE. Almost Internists: Analysis of Students Who Considered Internal Medicine but Chose Other Fields. Academic Medicine 2011, 86: 194-200. PMID: 21169784, DOI: 10.1097/acm.0b013e3182045ee5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceCareer ChoiceClinical ClerkshipCross-Sectional StudiesDelivery of Health CareEducation, Medical, UndergraduateFactor Analysis, StatisticalFemaleHumansInternal MedicineLogistic ModelsMaleSpecializationStudents, MedicalSurveys and QuestionnairesUnited StatesWorkforceConceptsEducational experienceCareer choiceCareer decisionsFourth-year medical studentsMedical student career choiceAnalysis of studentsNumber of studentsStudents' career choicesInternal medicineIM clerkshipStudent characteristicsMedical studentsU.S. institutionsStudentsIntellectual challengePatient's internistCareerAuthors' modelImportant underpinningExperienceChoosersPolicy makersSpecialtiesPercentage of varianceClerkship
2008
Factors Associated With Medical Students' Career Choices Regarding Internal Medicine
Hauer KE, Durning SJ, Kernan WN, Fagan MJ, Mintz M, O’Sullivan P, Battistone M, DeFer T, Elnicki M, Harrell H, Reddy S, Boscardin CK, Schwartz MD. Factors Associated With Medical Students' Career Choices Regarding Internal Medicine. JAMA 2008, 300: 1154-1164. PMID: 18780844, DOI: 10.1001/jama.300.10.1154.Peer-Reviewed Original ResearchConceptsStudents' career choicesCareer choiceEducational experienceCareer decision makingIM clerkshipMedical studentsFourth-year medical studentsMedical student career choiceGeneral internal medicineUS medical schoolsMedical student interestSubspecialty internal medicineInternal medicineStudent interestPrivate schoolsUS physician workforceMedical schoolsFavorable impressionStudentsCareerPhysician workforcePractice environmentClerkshipFavorable feelingsSchoolsDisagreement Between Students and Preceptors Regarding the Value of Teaching Behaviors for Ambulatory Care Settings
Kernan WN, Hershman W, Alper EJ, Lee MY, Viscoli CM, Perry JR, O'Connor PG. Disagreement Between Students and Preceptors Regarding the Value of Teaching Behaviors for Ambulatory Care Settings. Teaching And Learning In Medicine 2008, 20: 143-150. PMID: 18444201, DOI: 10.1080/10401330801991667.Peer-Reviewed Original ResearchConceptsPercentage of studentsTeaching behaviorsTeaching effectivenessU.S. schoolsClinical instructionMedical studentsStudentsPreceptorsDelegate responsibilityAmbulatory care settingsEarly negotiationsMutual satisfactionSchoolsInstructionLearningHistory takingAmbulatory careResponsibilityDiscussionRespondentsSatisfactionNegotiationsPurposeSettingTaking
2005
Major Risk Factors for Intracerebral Hemorrhage in the Young Are Modifiable
Feldmann E, Broderick JP, Kernan WN, Viscoli CM, Brass LM, Brott T, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Intracerebral Hemorrhage in the Young Are Modifiable. Stroke 2005, 36: 1881-1885. PMID: 16081867, DOI: 10.1161/01.str.0000177480.62341.6b.Peer-Reviewed Original ResearchConceptsPrimary intracerebral hemorrhageIntracerebral hemorrhageMajor risk factorRisk factorsHemorrhagic strokeCase subjectsIndependent risk factorHistory of strokeCurrent cigarette smokingCase-control studyType of strokeMultivariate regression analysisCigarette smokingStroke ProjectControl subjectsStructural lesionsArteriovenous malformationsBrain lesionsEligibility criteriaStrokeYoung menAlcoholic drinksFurther studiesHemorrhageMenopauseAssociation between Impaired Insulin Sensitivity and Stroke
Bravata DM, Wells CK, Kernan WN, Concato J, Brass LM, Gulanski BI. Association between Impaired Insulin Sensitivity and Stroke. Neuroepidemiology 2005, 25: 69-74. PMID: 15947493, DOI: 10.1159/000086286.Peer-Reviewed Original ResearchConceptsHomeostasis model assessmentInsulin sensitivityGlycemic controlMultivariable logistic regression analysisStroke risk factorsLower insulin sensitivityThird National HealthImpaired insulin sensitivityLogistic regression analysisStroke historyInsulin resistancePlasma insulinPlasma glucoseRisk factorsNational HealthNutrition SurveyModel assessmentStrokeRegression analysisAssociationParticipantsClaudicationInsulinRacial Disparities in Stroke Risk Factors
Bravata DM, Wells CK, Gulanski B, Kernan WN, Brass LM, Long J, Concato J. Racial Disparities in Stroke Risk Factors. Stroke 2005, 36: 1507-1511. PMID: 15961710, DOI: 10.1161/01.str.0000170991.63594.b6.Peer-Reviewed Original ResearchConceptsStroke risk factorsRisk factorsStroke historyHigh prevalenceLow high-density lipoprotein cholesterolHigher C-reactive proteinHigh-density lipoprotein cholesterolCommunity-dwelling stroke survivorsC-reactive proteinThird National HealthSevere strokeLipoprotein cholesterolMyocardial infarctionNational HealthStroke survivorsNutrition SurveyHigh incidenceUS populationStrokeOlder ageCross-sectional samplePrevalenceRacial disparitiesEthnic differencesAssociation
2004
Two measures of insulin sensitivity provided similar information in a U.S. population
Bravata DM, Wells CK, Concato J, Kernan WN, Brass LM, Gulanski BI. Two measures of insulin sensitivity provided similar information in a U.S. population. Journal Of Clinical Epidemiology 2004, 57: 1214-1217. PMID: 15567640, DOI: 10.1016/j.jclinepi.2004.05.001.Peer-Reviewed Original ResearchAssessing the Teaching Behaviors of Ambulatory Care Preceptors
Kernan WN, Holmboe E, O'Connor PG. Assessing the Teaching Behaviors of Ambulatory Care Preceptors. Academic Medicine 2004, 79: 1088-1094. PMID: 15504778, DOI: 10.1097/00001888-200411000-00017.Peer-Reviewed Original Research
2003
Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable
Broderick JP, Viscoli CM, Brott T, Kernan WN, Brass LM, Feldmann E, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable. Stroke 2003, 34: 1375-1381. PMID: 12764233, DOI: 10.1161/01.str.0000074572.91827.f4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionBody Mass IndexCase-Control StudiesCocaine-Related DisordersCohort StudiesComorbidityCooperative BehaviorFemaleHumansHypertensionLogistic ModelsMaleMiddle AgedOdds RatioPhenylpropanolamineRisk FactorsSex DistributionSmokingStrokeSubarachnoid HemorrhageThinnessUnited StatesConceptsAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageRisk factorsLower body mass indexIndependent risk factorCurrent cigarette smokersPrevalent risk factorsBody mass indexMajor risk factorCase-control studyYears of ageRandom digit dialingWarrants further studyHemorrhagic strokeIntracerebral hemorrhageCigarette smokersMass indexPreventable diseaseWomen 18Multivariable modelFamily historyCase subjectsAssociation of caffeineCocaine useHemorrhageUse of Ephedra-containing products and risk for hemorrhagic stroke
Morgenstern LB, Viscoli CM, Kernan WN, Brass LM, Broderick JP, Feldmann E, Wilterdink JL, Brott T, Horwitz RI. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003, 60: 132-135. PMID: 12525737, DOI: 10.1212/01.wnl.0000042092.20411.5b.Peer-Reviewed Original Research
2001
A Quality-of-Life Instrument for Young Hemorrhagic Stroke Patients
Hamedani A, Wells C, Brass L, Kernan W, Viscoli C, Maraire J, Awad I, Horwitz R. A Quality-of-Life Instrument for Young Hemorrhagic Stroke Patients. Stroke 2001, 32: 687-695. PMID: 11239188, DOI: 10.1161/01.str.32.3.687.Peer-Reviewed Original ResearchConceptsOutcome measuresHemorrhagic strokeQuality of lifeValid QOL instrumentHemorrhagic stroke patientsHemorrhagic stroke survivorsAvailable outcome measuresDistinct subject groupsYounger patientsStroke patientsPatient interviewsNeurological impairmentStroke survivorsMotor functionQOL instrumentsLife instrumentsMortality ratePatient's lifeHigh initial mortality rateStrokePatientsCeiling effectsSubject groupsInitial mortality rateInternal consistency
2000
Phenylpropanolamine and the Risk of Hemorrhagic Stroke
Kernan W, Viscoli C, Brass L, Broderick J, Brott T, Feldmann E, Morgenstern L, Wilterdink J, Horwitz R. Phenylpropanolamine and the Risk of Hemorrhagic Stroke. New England Journal Of Medicine 2000, 343: 1826-1832. PMID: 11117973, DOI: 10.1056/nejm200012213432501.Peer-Reviewed Original ResearchConceptsUse of coughHemorrhagic strokeAppetite suppressantsCold remediesControl subjectsOdds ratioIndependent risk factorCase-control studyYears of ageRandom digit dialingIntracerebral hemorrhageCase reportRisk factorsBrain lesionsWomen 18CoughEligibility criteriaStrokeU.S. hospitalsPhenylpropanolamineWomenPatientsMenRiskAssociationEffective teaching for preceptors of ambulatory care: a survey of medical students
Kernan W, Lee M, Stone S, Freudigman K, O’Connor P. Effective teaching for preceptors of ambulatory care: a survey of medical students. The American Journal Of Medicine 2000, 108: 499-502. PMID: 10781784, DOI: 10.1016/s0002-9343(00)00301-6.Peer-Reviewed Original Research
1989
Ceftriaxone Compared with Cefotaxime for Serious Bacterial Infections
Smith C, Petty B, Hendrix C, Kernan W, Garver P, Fox K, Beamer A, Carbone K, Threlkeld M, Lietman P. Ceftriaxone Compared with Cefotaxime for Serious Bacterial Infections. The Journal Of Infectious Diseases 1989, 160: 442-447. PMID: 2668428, DOI: 10.1093/infdis/160.3.442.Peer-Reviewed Original ResearchConceptsSerious bacterial infectionsBacterial infectionsDouble-blind clinical trialSuspected serious bacterial infectionResponse rateCefotaxime 2 gCeftriaxone 2 gDose of ceftriaxoneTreatment groupsDose of cefotaximeFrequency of diarrheaClinical responseAnaerobic infectionsProthrombin timeCeftriaxoneClinical trialsCefotaximeInfecting organismInfectionAdverse effectsDoseTreatmentDaysThrombophlebitisProthrombin