2013
The Immunopathogenesis of Cirrhosis
Gao B, Friedman S, Mehal W. The Immunopathogenesis of Cirrhosis. 2013, 413-424. DOI: 10.1007/978-3-319-02096-9_28.Peer-Reviewed Original ResearchHepatocellular carcinomaProgressive liver injuryChronic liver diseaseNatural killer cellsImmune cell subsetsAltered hepatic functionInnate immune responseWound healing responseViral hepatitisLiver injuryFibrosis progressionKiller cellsLiver diseaseAutoimmune diseasesCell subsetsChronic injuryHepatic fibrosisFibrogenic responseFibrosis resolutionHepatic functionHepatic parenchymaVascular remodelingImmune responseHepatocellular apoptosisBlood flow
2010
Cell Death and Fibrogenesis
Mehal W, Imaeda A. Cell Death and Fibrogenesis. Seminars In Liver Disease 2010, 30: 226-231. PMID: 20665375, PMCID: PMC3219753, DOI: 10.1055/s-0030-1255352.BooksConceptsHepatic stellate cellsQuiescent hepatic stellate cellsChronic liver injuryNatural killer cellsCell deathHIV infectionLiver injuryNK cellsKiller cellsAntifibrotic effectsImmune suppressionImmune cellsProfibrotic effectsStellate cellsHepatocyte deathHSC apoptosisDeathCellular deathFibrosisCellular debrisMatrix depositionHSC deathSurvival signalsApoptotic bodiesProapoptotic signals