2010
Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack
Bravata DM, Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Knight HJ, Lo A, Richerson GB, Gorman M, Williams LS, Brass LM, Agostini J, Mohsenin V, Roux F, Yaggi HK. Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack. Stroke 2010, 41: 1464-1470. PMID: 20508184, PMCID: PMC4567557, DOI: 10.1161/strokeaha.109.566745.Peer-Reviewed Original ResearchConceptsRecurrent vascular eventsVascular event ratesIntervention patientsSleep apneaTIA patientsVascular eventsContinuous positive airway pressure (CPAP) adherenceAcute transient ischemic attackTransient ischemic attack patientsContinuous positive airway pressurePositive airway pressure adherenceEvent ratesTransient ischemic attackPositive airway pressureCongestive heart failureMajority of patientsSleep apnea patientsIschemic attackRecurrent TIAAirflow obstructionAirway pressureControl patientsCPAP useHeart failureMyocardial infarction
2006
Chronic obstructive pulmonary disease and sleep: the interaction.
Urbano F, Mohsenin V. Chronic obstructive pulmonary disease and sleep: the interaction. Panminerva Medica 2006, 48: 223-30. PMID: 17215794.Peer-Reviewed Original ResearchMeSH KeywordsHumansHypoxiaPolysomnographyPrevalencePulmonary Disease, Chronic ObstructiveRespirationSleepSleep Apnea SyndromesConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseasePulmonary diseaseSevere chronic obstructive pulmonary diseaseRespiratory muscle fatigueRight ventricular overloadElevated pulmonary pressuresUpper airway resistanceFourth leading causeFunctional residual capacityGoal of therapyOxyhemoglobin dissociation curveProfound adverse effectsMillion adultsResultant hypoxemiaOxygen desaturationPulmonary rehabilitationPulmonary pressureVentricular overloadAirway resistanceRespiratory driveSmoking cessationMorning fatigueLung mechanicsSleep disturbances
2001
Sleep-Related Breathing Disorders and Risk of Stroke
Mohsenin V. Sleep-Related Breathing Disorders and Risk of Stroke. Stroke 2001, 32: 1271-1278. PMID: 11387486, DOI: 10.1161/01.str.32.6.1271.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersTransient ischemic attackRisk of strokeBreathing disordersRisk factorsSleep apnea disorderIschemic attackApnea disorderHematologic changesHigh prevalenceNormal sleep stateModifiable risk factorsPresence of hypertensionRecent large epidemiological studiesPossible pathogenetic mechanismsLarge epidemiological studiesDiurnal hypertensionCerebral perfusionSignificant morbidityCerebral hemodynamicsPathogenetic mechanismsEpidemiological studiesStrokeHypertensionPatients
2000
Sleep-related breathing disorders and cardiovascular disease
Roux F, D’Ambrosio C, Mohsenin V. Sleep-related breathing disorders and cardiovascular disease. The American Journal Of Medicine 2000, 108: 396-402. PMID: 10759096, DOI: 10.1016/s0002-9343(00)00302-8.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersBreathing disordersRisk factorsUpper airway resistance syndromeIndependent risk factorMajority of patientsMajor health problemPulmonary hypertensionSympathetic toneBaroreflex controlIntermittent hypoxiaExcessive daytimeSleep apneaCerebrovascular diseaseResistance syndromeEarly recognitionCardiovascular functionCardiovascular diseaseEpidemiologic studiesNeuropsychological dysfunctionHealth problemsMemory impairmentPoor work performanceDisordersHypertension
1999
Quality of Life in Patients with Obstructive Sleep Apnea Effect of Nasal Continuous Positive Airway Pressure—A Prospective Study
D’Ambrosio C, Bowman T, Mohsenin V. Quality of Life in Patients with Obstructive Sleep Apnea Effect of Nasal Continuous Positive Airway Pressure—A Prospective Study. CHEST Journal 1999, 115: 123-129. PMID: 9925072, DOI: 10.1378/chest.115.1.123.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaQuality of lifeMental healthMedical Outcomes Study Short Form-36 questionnaireNasal continuous positive airway pressure treatmentEffect of OSAContinuous positive airway pressure (CPAP) treatmentNasal continuous positive airway pressureDiagnosis of OSASocial functioningPositive airway pressure treatmentContinuous positive airway pressureShort Form-36 questionnaireEffect of nCPAPPositive airway pressureRespiratory disturbance indexSleep-disordered breathingBody mass indexEvents/hGender-matched populationCase series analysisSeverity of diseaseMagnitude of improvementNCPAP levelNCPAP therapy
1998
SLEEP IN ASTHMA
D'Ambrosio C, Mohsenin V. SLEEP IN ASTHMA. Clinics In Chest Medicine 1998, 19: 127-137. PMID: 9554223, DOI: 10.1016/s0272-5231(05)70437-8.Peer-Reviewed Original Research
1995
Sleep apnea in patients with hemispheric stroke
Mohsenin V, Valor R. Sleep apnea in patients with hemispheric stroke. Archives Of Physical Medicine And Rehabilitation 1995, 76: 71-76. PMID: 7811179, DOI: 10.1016/s0003-9993(95)80046-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCase-Control StudiesCerebrovascular DisordersFemaleHumansMaleMiddle AgedSleep Apnea SyndromesSleep StagesConceptsSleep-disordered breathingHemispheric strokeCerebral symptomsSleep apneaStroke patientsRapid eye movement (REM) sleepArterial oxygen desaturationComplications of strokePresence of hypertensionRespiratory disturbance indexBody mass indexAbnormal sleep architectureEye movement sleepSlow-wave sleepOxygen desaturationGroups of subjectsBrainstem lesionsCerebrovascular accidentCerebral strokeMass indexRespiratory disturbancesRespiratory eventsMovement sleepSleep architecturePrior history