2016
Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence
Morgan PT, Angarita GA, Canavan S, Pittman B, Oberleitner L, Malison RT, Mohsenin V, Hodges S, Easton C, McKee S, Bessette A, Forselius E. Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence. Drug And Alcohol Dependence 2016, 160: 49-56. PMID: 26777774, PMCID: PMC4767553, DOI: 10.1016/j.drugalcdep.2015.12.004.Peer-Reviewed Original ResearchConceptsUrine toxicology screenModafinil treatmentSlow-wave sleepClinical outcomesOutpatient treatmentToxicology screenUrine screensInpatient settingInpatient treatmentSleep timeCocaine dependencePrimary clinical outcomeWeekly cognitive behavioral therapyCocaine usersImproved clinical outcomesPolysomnographic sleep recordingsChronic cocaine useChronic cocaine usersHigh rateCognitive behavioral therapyCocaine-dependent participantsSleep architectureOutpatient phaseEffective treatmentDays abstinent
2006
Chronic obstructive pulmonary disease and sleep: the interaction.
Urbano F, Mohsenin V. Chronic obstructive pulmonary disease and sleep: the interaction. Panminerva Medica 2006, 48: 223-30. PMID: 17215794.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseasePulmonary diseaseSevere chronic obstructive pulmonary diseaseRespiratory muscle fatigueRight ventricular overloadElevated pulmonary pressuresUpper airway resistanceFourth leading causeFunctional residual capacityGoal of therapyOxyhemoglobin dissociation curveProfound adverse effectsMillion adultsResultant hypoxemiaOxygen desaturationPulmonary rehabilitationPulmonary pressureVentricular overloadAirway resistanceRespiratory driveSmoking cessationMorning fatigueLung mechanicsSleep disturbances
2001
Sleep-Related Breathing Disorders and Risk of Stroke
Mohsenin V. Sleep-Related Breathing Disorders and Risk of Stroke. Stroke 2001, 32: 1271-1278. PMID: 11387486, DOI: 10.1161/01.str.32.6.1271.Peer-Reviewed Original ResearchConceptsSleep-related breathing disordersTransient ischemic attackRisk of strokeBreathing disordersRisk factorsSleep apnea disorderIschemic attackApnea disorderHematologic changesHigh prevalenceNormal sleep stateModifiable risk factorsPresence of hypertensionRecent large epidemiological studiesPossible pathogenetic mechanismsLarge epidemiological studiesDiurnal hypertensionCerebral perfusionSignificant morbidityCerebral hemodynamicsPathogenetic mechanismsEpidemiological studiesStrokeHypertensionPatients
1998
SLEEP IN ASTHMA
D'Ambrosio C, Mohsenin V. SLEEP IN ASTHMA. Clinics In Chest Medicine 1998, 19: 127-137. PMID: 9554223, DOI: 10.1016/s0272-5231(05)70437-8.Peer-Reviewed Original Research
1994
Daytime oxygen saturation does not predict nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease
Mohsenin V, Guffanti E, Hilbert J, Ferranti R. Daytime oxygen saturation does not predict nocturnal oxygen desaturation in patients with chronic obstructive pulmonary disease. Archives Of Physical Medicine And Rehabilitation 1994, 75: 285-289. PMID: 8129580, DOI: 10.1016/0003-9993(94)90030-2.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseNocturnal oxygen desaturationObstructive pulmonary diseaseOxygen desaturationAwake SaO2Nocturnal hypoxemiaPulmonary diseaseOxygen saturationDaytime oxygen saturationArterial oxygen saturationControl of breathingNocturnal SaO2COPD patientsPulmonary hypertensionAwake patientsPathologic mechanismsIndividual patientsNocturnal oximetryCardiac arrhythmiasPatientsSaO2HypoxemiaDesaturationOximetryDisease