Circulating fibrocytes: collagen-secreting cells of the peripheral blood
Quan TE, Cowper S, Wu SP, Bockenstedt LK, Bucala R. Circulating fibrocytes: collagen-secreting cells of the peripheral blood. The International Journal Of Biochemistry & Cell Biology 2004, 36: 598-606. PMID: 15010326, DOI: 10.1016/j.biocel.2003.10.005.Peer-Reviewed Original ResearchConceptsNephrogenic fibrosing dermopathyAntigen-presenting cellsNaïve T cellsNew disease entityPresentation of antigensImportant etiopathogenic roleRenal insufficiencyUnique cell populationFibrosing disorderLocal tissue environmentImmunological markersInflammatory cytokinesPeripheral bloodEtiopathogenic roleFibrotic lesionsGranuloma formationAntigen presentationDisease entityT cellsHypertrophic scarsMatrix metalloproteinasesRemodeling responseFibrocytesContractile myofibroblastsCollagen-secreting cellsDefective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus Erythematosus
Kang I, Quan T, Nolasco H, Park SH, Hong MS, Crouch J, Pamer EG, Howe JG, Craft J. Defective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus Erythematosus. The Journal Of Immunology 2004, 172: 1287-1294. PMID: 14707107, DOI: 10.4049/jimmunol.172.2.1287.Peer-Reviewed Original ResearchMeSH KeywordsAdultB-Lymphocyte SubsetsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytomegalovirusEpitopes, T-LymphocyteEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansLeukocytes, MononuclearLupus Erythematosus, SystemicLymphocyte CountMaleMiddle AgedSeverity of Illness IndexViral LoadVirus LatencyConceptsSystemic lupus erythematosusEBV viral loadT cell responsesViral loadT cellsIFN-gammaCell responsesEBV infectionLupus erythematosusHealthy controlsEBV-specific T-cell responsesVirus-specific T cell responsesLatent Epstein-Barr virus (EBV) infectionEBV-specific immune responsesEpstein-Barr virus infectionAltered T-cell responsesDefective controlFrequency of CD69HLA-A2 tetramersTetramer-positive CD8Latent EBV infectionEBV-specificImmunosuppressive medicationsDisease activityLupus patients