2017
The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial
Gill TM, Beavers DP, Guralnik JM, Pahor M, Fielding RA, Hauser M, Manini TM, Marsh AP, McDermott MM, Newman AB, Allore HG, Miller ME, for the LIFE Study Investigators. The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial. BMC Medicine 2017, 15: 65. PMID: 28347337, PMCID: PMC5368996, DOI: 10.1186/s12916-017-0824-6.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityPhysical activity programPhysical activity interventionsPhysical activityActivity programOlder personsHazard ratioActivity interventionsFunctional limitationsModerate-intensity physical activity programCommunity-living older personsStructured physical activity programHealth education groupStructured physical activityHealth education programsIndependent mobilityAcute illnessLifestyle interventionHospital exposureElders StudyParallel groupSedentary personsUS CentersHospitalizationSustained benefit
2016
Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial.
Gill TM, Guralnik JM, Pahor M, Church T, Fielding RA, King AC, Marsh AP, Newman AB, Pellegrini CA, Chen SH, Allore HG, Miller ME. Effect of Structured Physical Activity on Overall Burden and Transitions Between States of Major Mobility Disability in Older Persons: Secondary Analysis of a Randomized Trial. Annals Of Internal Medicine 2016, 165: 833-840. PMID: 27669457, PMCID: PMC5476905, DOI: 10.7326/m16-0529.Peer-Reviewed Original ResearchConceptsMajor mobility disabilityStructured physical activity programPhysical activity programPhysical activityMobility disabilityHealth educationActivity programStructured physical activityHealth education interventionNational InstituteOnset of disabilityQuality of lifeDisability episodeTreat principleRandomized trialsPatient assessmentRisk ratioOverall burdenProportion of assessmentsSedentary personsFunctional limitationsU.S. CentersEnhanced recoverySecondary analysisOlder personsEffect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study)
Gill TM, Pahor M, Guralnik JM, McDermott MM, King AC, Buford TW, Strotmeyer ES, Nelson ME, Sink KM, Demons JL, Kashaf SS, Walkup MP, Miller ME. Effect of structured physical activity on prevention of serious fall injuries in adults aged 70-89: randomized clinical trial (LIFE Study). The BMJ 2016, 352: i245. PMID: 26842425, PMCID: PMC4772786, DOI: 10.1136/bmj.i245.Peer-Reviewed Original ResearchConceptsSerious fall injuriesPhysical activity programHealth education programsStructured physical activity programSedentary older peopleFall injuriesHospital admissionFunctional limitationsActivity programOlder peopleModerate-intensity physical activity programShort Physical Performance Battery scorePhysical Performance Battery scoreNon-vertebral fracturesPrespecified secondary outcomesPhysical activity groupRelated hospital admissionsHealth education groupStructured physical activityBalance training activitiesRate of fallSecondary outcomesStretching exercisesIntervention assignmentClinical trials