2023
Serum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy
Agampodi S, Agampodi T, Amarasinghe G, Warnasekara J, Hettiarachchi A, Jayasinghe I, Koralegedara I, Abeyrathna P, Srimantha S, de Silva F, Gunarathne S, Wickramasinghe N. Serum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy. PLOS Global Public Health 2023, 3: e0000443. PMID: 36962935, PMCID: PMC10021427, DOI: 10.1371/journal.pgph.0000443.Peer-Reviewed Original ResearchGlomerular filtration rateWeeks of gestationRenal functionPregnant womenNonpregnant womenSerum creatinineSecond trimesterEarly pregnancyFiltration rateClinical practiceCommunity-based prospective cohort studyProspective population-based studyPre-existing medical conditionsProspective cohort studyHealthy pregnant womenCommunity-based cohortPopulation-based studyDifferent age strataMean eGFRCohort studyNewborn outcomesNonpregnant groupPregnancy cohortFirst trimesterMean SCr
2021
Clinical spectrum of endemic leptospirosis in relation to cytokine response
Dahanayaka NJ, Agampodi SB, Seneviratna I, Warnasekara J, Rajapakse R, Ranathunga K, Matthias M, Vinetz JM. Clinical spectrum of endemic leptospirosis in relation to cytokine response. PLOS ONE 2021, 16: e0261025. PMID: 34879100, PMCID: PMC8654203, DOI: 10.1371/journal.pone.0261025.Peer-Reviewed Original ResearchConceptsCytokine responsesLeptospirosis patientsClinical spectrumHigher IL-13 levelsHigher IL-5Acute kidney injuryHigher serum creatinineIL-13 levelsSerum cytokine levelsIL-6 levelsUniversity Teaching HospitalMultiplex cytokine kitKidney injuryLung involvementCytokine levelsSerum creatinineAcute phaseCytokine kitIL-1βAcute samplesConvalescence periodIL-8IL-5Prognostic informationEndemic settings