2012
Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets
Mukhopadhyay S, Nair S, Ghosh S. Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets. FEMS Microbiology Reviews 2012, 36: 463-485. PMID: 22092372, DOI: 10.1111/j.1574-6976.2011.00302.x.Peer-Reviewed Original ResearchConceptsMajor health problemHost immune responseEmergence of strainsDrug targetsDendritic cellsEffective drug targetsInhibition of apoptosisImmune responseNew drug targetsHealth problemsLipid metabolismMultiple drugsTuberculosisComplex etiologyMycobacterium tuberculosisIntracellular life styleTranscriptome signaturesVirulence mechanismsGenome-wide expression profilingDrugsAntibiotic drugsExpression profilingProtein secretionLife stylePoor understanding
2008
The PPE Protein Rv1196 of Mycobacterium tuberculosis Exploits the TLR2 Signaling in Macrophages Eliciting an Anti-Inflammatory Response by Producing IL-10
Mukhopadhyay S, Nair S, Mande S, Hasnain S. The PPE Protein Rv1196 of Mycobacterium tuberculosis Exploits the TLR2 Signaling in Macrophages Eliciting an Anti-Inflammatory Response by Producing IL-10. International Journal Of Infectious Diseases 2008, 12: e477. DOI: 10.1016/j.ijid.2008.05.1351.Peer-Reviewed Original Research