2022
Long-term quantitative assessment of anti-SARS-CoV-2 spike protein immunogenicity (QUASI) after COVID-19 vaccination in older people living with HIV (PWH)
Tuan JJ, Zapata H, Barakat L, Andrews L, Behnegar A, Kim YW, Kayani J, Mutic S, Ryall L, Turcotte B, Critch-Gilfillan T, Zhao M, Salahuddin S, Gupta S, Sutton R, Friedland G, Emu B, Ogbuagu O. Long-term quantitative assessment of anti-SARS-CoV-2 spike protein immunogenicity (QUASI) after COVID-19 vaccination in older people living with HIV (PWH). BMC Infectious Diseases 2022, 22: 744. PMID: 36131232, PMCID: PMC9491266, DOI: 10.1186/s12879-022-07737-0.Peer-Reviewed Original ResearchConceptsT cell responsesAnti-spike IgGVisit 3SARS-CoV-2Older PWHVisit 2Immune responseSingle-center longitudinal observational studyVirus-specific T cell responsesVaccine-induced humoral immunityLong-term protective immunityT cell immune responsesOlder peopleMedian age 61RBD IgG levelsPrimary study outcomeCOVID-19 vaccinationImmune response evaluationLongitudinal observational studyCOVID-19 vaccineWilcoxon signed-rank testBNT162b2 boosterBNT162b2 vaccinationCD8 responsesDetectable CD4Clinical and virologic factors associated with outcomes of COVID‐19 before and after vaccination among Veterans: Retrospective analysis from six New England states
Lee M, Cosentino D, Kyriakides TC, Cavallaro T, Stack G, Gupta S. Clinical and virologic factors associated with outcomes of COVID‐19 before and after vaccination among Veterans: Retrospective analysis from six New England states. Journal Of Hospital Medicine 2022, 17: 534-538. PMID: 35661577, PMCID: PMC9348310, DOI: 10.1002/jhm.12852.Peer-Reviewed Original ResearchConceptsCOVID-19Intensive care unit admissionVeterans Administration Healthcare SystemCare unit admissionNonpsychiatric hospitalizationsVirologic factorsFull vaccinationUnit admissionICU careClinical outcomesPoor outcomeMean ageRetrospective analysisD614G mutationHealthcare systemVeteransNew England statesHospitalizationOlder cohortOutcomesViral epidemiologyVaccinationDemographic factorsG mutationAge
2019
Native Joint Septic Arthritis: Comparison of Outcomes with Medical and Surgical Management.
Harada K, McConnell I, DeRycke EC, Holleck JL, Gupta S. Native Joint Septic Arthritis: Comparison of Outcomes with Medical and Surgical Management. Southern Medical Journal 2019, 112: 238-243. PMID: 30943544, DOI: 10.14423/smj.0000000000000958.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnkle JointAnti-Bacterial AgentsArthritis, InfectiousArthrocentesisArthroscopyCandidiasisDrainageElbow JointFemaleGram-Negative Bacterial InfectionsGram-Positive Bacterial InfectionsHip JointHospitalizationHumansKnee JointMaleMiddle AgedRange of Motion, ArticularRecovery of FunctionRetrospective StudiesShoulder JointStaphylococcal InfectionsSternoclavicular JointStreptococcal InfectionsTertiary Care CentersWrist JointConceptsSeptic arthritisSurgical managementCases of SADiagnosis of SARetrospective single-center studyNative joint septic arthritisSingle-center studyTertiary care hospitalLong-term outcomesLength of stayShort-term rehabilitationComparison of outcomesNative joint infectionsCare hospitalMedical managementJoint infectionRehabilitation unitInclusion criteriaEvaluated outcomesNative jointProsthetic jointsFull recoveryPatientsOutcomesSame joint
2017
The “Hand-in” Project
Holleck JL, Gunderson CG, Antony SM, Gupta S, Chang JJ, Merchant N, Lin S, Federman DG. The “Hand-in” Project. Southern Medical Journal 2017, 110: 694-698. PMID: 29100218, DOI: 10.14423/smj.0000000000000724.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmbulatory CareComputer SecurityContinuity of Patient CareElectronic MailEmergency Service, HospitalFemaleHospitalistsHospitalizationHumansInterprofessional RelationsMalePatient ReadmissionPhysicians, Primary CareProspective StudiesUnited StatesUnited States Department of Veterans Affairs
2016
Diagnostic accuracy of methicillin-resistant Staphylococcus aureus nasal colonization to predict methicillin-resistant S aureus soft tissue infections
Gunderson CG, Holleck JL, Chang JJ, Merchant N, Lin S, Gupta S. Diagnostic accuracy of methicillin-resistant Staphylococcus aureus nasal colonization to predict methicillin-resistant S aureus soft tissue infections. American Journal Of Infection Control 2016, 44: 1176-1177. PMID: 27311510, DOI: 10.1016/j.ajic.2016.03.039.Peer-Reviewed Original ResearchConceptsSoft tissue infectionsMRSA infectionTissue infectionsPrevalence populationsMethicillin-resistant Staphylococcus aureus nasal colonizationMRSA soft tissue infectionsStaphylococcus aureus nasal colonizationHigh-prevalence populationsLow-prevalence populationsPositive likelihood ratioNegative likelihood ratioNasal MRSALikelihood ratioNasal colonizationClinical utilityInfectionDiagnostic accuracyAdmissionHospitalPopulationMRSAPrevalenceClinical characteristics and outcomes of veterans hospitalised with purulent soft tissue infections with and without systemic signs of infection
Gunderson CG, Holleck J, Chang JJ, Lin S, Merchant N, Gupta S. Clinical characteristics and outcomes of veterans hospitalised with purulent soft tissue infections with and without systemic signs of infection. Infectious Diseases 2016, 48: 503-508. PMID: 26950290, DOI: 10.3109/23744235.2016.1154599.Peer-Reviewed Original ResearchConceptsPurulent soft tissue infectionsSoft tissue infectionsTissue infectionsClinical characteristicsSevere sepsisSIRS groupSystemic signsSIR groupSystemic inflammatory response syndrome criteriaBroad Gram-negative activityMethods Retrospective cohort studyOutcomes of veteransAcute kidney injuryRetrospective cohort studyEpisodes of bacteremiaTime of hospitalisationCohort of patientsMajority of patientsMost clinical characteristicsUse of antibioticsMore bacteremiaKidney injuryShorter hospitalisationSyndrome criteriaCohort study
2009
Hepatitis B Virus Infection in US Correctional Facilities: A Review of Diagnosis, Management, and Public Health Implications
Gupta S, Altice FL. Hepatitis B Virus Infection in US Correctional Facilities: A Review of Diagnosis, Management, and Public Health Implications. Journal Of Urban Health 2009, 86: 263-279. PMID: 19184447, PMCID: PMC2648882, DOI: 10.1007/s11524-008-9338-z.BooksConceptsChronic viral infectionsHepatitis B virus infectionB virus infectionReview of diagnosisHBV infectionViral infectionVirus infectionMedical careChronic HBV infectionChronic hepatitis BChronic medical conditionsComprehensive medical carePublic health burdenPublic health impactHigh-risk behaviorsPublic health implicationsProvision of vaccinationUS correctional facilitiesCorrectional settingsHBV vaccineHepatitis BViral hepatitisTreatment guidelinesChronic infectionChronic illness
2008
Persistent and Relapsing Babesiosis in Immunocompromised Patients
Krause PJ, Gewurz BE, Hill D, Marty FM, Vannier E, Foppa IM, Furman RR, Neuhaus E, Skowron G, Gupta S, McCalla C, Pesanti EL, Young M, Heiman D, Hsue G, Gelfand JA, Wormser GP, Dickason J, Bia FJ, Hartman B, Telford SR, Christianson D, Dardick K, Coleman M, Girotto JE, Spielman A. Persistent and Relapsing Babesiosis in Immunocompromised Patients. Clinical Infectious Diseases 2008, 46: 370-376. PMID: 18181735, DOI: 10.1086/525852.Peer-Reviewed Original ResearchConceptsCase patientsAntibabesial treatmentClinical courseControl subjectsBlood smearsRetrospective case-control studyOptimal treatment regimenStandard antimicrobial therapyMalaria-like illnessBabesia microti infectionMost cases patientsCase-control studyCourse of therapyB-cell lymphomaAdministration of atovaquoneImmunologic statusStandard therapyAntimicrobial regimenSuch patientsTreatment regimenMicroti infectionAntimicrobial therapyPersistent infectionCell lymphomaAcute babesiosis