2023
Quantitative Prediction of Right Ventricular Size and Function From the ECG
Duong S, Vaid A, My V, Butler L, Lampert J, Pass R, Charney A, Narula J, Khera R, Sakhuja A, Greenspan H, Gelb B, Do R, Nadkarni G. Quantitative Prediction of Right Ventricular Size and Function From the ECG. Journal Of The American Heart Association 2023, 13: e031671. PMID: 38156471, PMCID: PMC10863807, DOI: 10.1161/jaha.123.031671.Peer-Reviewed Original Research
2021
Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries
Fudim M, Zhong L, Patel KV, Khera R, Abdelmalek MF, Diehl AM, McGarrah RW, Molinger J, Moylan CA, Rao VN, Wegermann K, Neeland IJ, Halm EA, Das SR, Pandey A. Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries. Journal Of The American Heart Association 2021, 10: e021654. PMID: 34755544, PMCID: PMC8751938, DOI: 10.1161/jaha.121.021654.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseIncident heart failureReduced ejection fractionFatty liver diseaseHeart failureEjection fractionMedicare beneficiariesHF subtypesLiver diseaseHigh riskBackground Nonalcoholic fatty liver diseaseBaseline NAFLDAssociation of NAFLDNew-onset heart failureConclusions PatientsCohort studyPrior diagnosisBlack patientsNinth RevisionKidney diseaseOutpatient claimsRisk factorsIndependent associationHigh burdenMedicare patients
2019
Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction
Angraal S, Mortazavi BJ, Gupta A, Khera R, Ahmad T, Desai NR, Jacoby DL, Masoudi FA, Spertus JA, Krumholz HM. Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction. JACC Heart Failure 2019, 8: 12-21. PMID: 31606361, DOI: 10.1016/j.jchf.2019.06.013.Peer-Reviewed Original ResearchConceptsHF hospitalizationRisk of mortalityEjection fractionBlood urea nitrogen levelsLogistic regressionPrevious HF hospitalizationHeart failure hospitalizationReduced ejection fractionReceiver-operating characteristic curveRisk of deathBody mass indexBlood urea nitrogenUrea nitrogen levelsHealth status dataMean c-statisticKCCQ scoresTOPCAT trialFailure hospitalizationHeart failureHemoglobin levelsMass indexC-statisticHospitalizationUrea nitrogenMortality
2018
Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis
Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis. JACC Heart Failure 2018, 6: 117-126. PMID: 29413366, PMCID: PMC8135913, DOI: 10.1016/j.jchf.2017.10.014.Peer-Reviewed Original ResearchMeSH KeywordsExercise TestExercise ToleranceHeart FailureHeart RateHumansStroke VolumeVentricular Function, LeftConceptsPulmonary capillary wedge pressureCapillary wedge pressurePeak oxygen uptakePooled analysisWedge pressureEchocardiographic parametersHeart failureExercise intoleranceExaggerated increaseReserve parametersControl groupLower peak oxygen uptakeRelative impairmentStroke volume reserveOxygen uptakeChronic HFpEFHemodynamic reserveExercise toleranceExercise capacityEjection fractionChronotropic reserveControl subjectsCardinal manifestationsHFpEFSignificant abnormalities