1996
Autoregulation of myocardial glycogen concentration during intermittent hypoxia
McNulty P, Ng C, Liu W, Jagasia D, Letsou G, Baldwin J, Soufer R. Autoregulation of myocardial glycogen concentration during intermittent hypoxia. American Journal Of Physiology 1996, 271: r311-r319. PMID: 8770128, DOI: 10.1152/ajpregu.1996.271.2.r311.Peer-Reviewed Original Research
1995
Comparison of sestamibi single-photon emission computed tomography with positron emission tomography for estimating left ventricular myocarclial viability
Soufer R, Dey H, Ng C, Zaret B. Comparison of sestamibi single-photon emission computed tomography with positron emission tomography for estimating left ventricular myocarclial viability. The American Journal Of Cardiology 1995, 75: 1214-1219. PMID: 7778542, DOI: 10.1016/s0002-9149(99)80765-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCoronary DiseaseDeoxyglucoseFluorine RadioisotopesFluorodeoxyglucose F18HumansMaleMiddle AgedMyocardial ContractionRadionuclide VentriculographyStroke VolumeTechnetium Tc 99m SestamibiTomography, Emission-ComputedTomography, Emission-Computed, Single-PhotonVentricular Function, LeftConceptsPositron emission tomographySestamibi single-photon emissionSingle photon emissionCoronary artery diseaseMyocardial viabilityInferior wallArtery diseaseEmission tomographyFDG positron emission tomographySubset of patientsRegional ejection fractionDiscordant segmentsNonviable segmentsEjection fractionMethoxyisobutyl isonitrileRadionuclide ventriculographySestamibi protocolBlood flowMyocardial segmentsPatientsViable segmentsFluorodeoxyglucoseMIBITomographyDiseaseRelationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study.
Soufer R, Dey H, Lawson A, Wackers F, Zaret B. Relationship between reverse redistribution on planar thallium scintigraphy and regional myocardial viability: a correlative PET study. Journal Of Nuclear Medicine 1995, 36: 180-7. PMID: 7830110.Peer-Reviewed Original ResearchConceptsPlanar thallium scintigraphyCardiac eventsThallium scintigraphyReverse redistributionChronic coronary artery diseasePET viabilityAbnormal regional wall motionPlanar thallium imagesMyocardial Infarction trialPercent of patientsFuture cardiac eventsFuture cardiovascular eventsCoronary artery diseaseFavorable clinical outcomeMyocardial metabolic activityRegional wall motion analysisRegional wall motionPercent of segmentsWall motion analysisPET criteriaCardiovascular eventsReperfusion therapyArtery diseaseClinical outcomesPrognostic value
1990
Coronary Flow Limits Right Ventricular Performance during Positive End-expiratory Pressure
Schulman D, Biondi J, Zohgbi S, Zaret B, Soufer R. Coronary Flow Limits Right Ventricular Performance during Positive End-expiratory Pressure. American Journal Of Respiratory And Critical Care Medicine 1990, 141: 1531-1537. PMID: 2190508, DOI: 10.1164/ajrccm/141.6.1531.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCardiac OutputCoronary CirculationCoronary DiseaseDogsFemaleMaleMyocardial ContractionPositive-Pressure RespirationStroke VolumeThermodilutionConceptsPositive end-expiratory pressureRight ventricular ejection fractionH2O positive end-expiratory pressureEnd-diastolic volumeRight ventricular performanceMyocardial blood flowRCA occlusionEnd-expiratory pressureBlood flowVentricular performanceRight ventricular myocardial blood flowRight coronary blood flowRight coronary artery occlusionVentricular myocardial blood flowVentricular ejection fractionCoronary blood flowCoronary artery occlusionEnd-ejection volumeArtery occlusionEjection fractionPressure-volume relationRCA flowExperimental modelOcclusion
1989
Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure
Schulman D, Biondi J, Matthay R, Zaret B, Soufer R. Differing responses in right and left ventricular filling, loading and volumes during positive end-expiratory pressure. The American Journal Of Cardiology 1989, 64: 772-777. PMID: 2679024, DOI: 10.1016/0002-9149(89)90763-7.Peer-Reviewed Original ResearchConceptsPeak filling rateEnd-diastolic volumeLV end-diastolic volumeEjection fractionLeft ventricularCardiac outputRV volumesLV volumesPositive end-expiratory pressure (PEEP) applicationRight ventricular ejection fractionRV end-diastolic volumePositive end-expiratory pressureGroup 1 patientsLow cardiac outputSystemic vascular resistanceVentricular ejection fractionCoronary artery diseaseLV ejection fractionRV ejection fractionEnd-expiratory pressureFilling rateVascular resistanceArtery diseaseBlood pressureVentricular function
1988
Recovery of severe ischemic ventricular dysfunction after coronary artery bypass grafting
Brill D, Deckelbaum L, Remetz M, Soufer R, Elefteriades J, Zaret B. Recovery of severe ischemic ventricular dysfunction after coronary artery bypass grafting. The American Journal Of Cardiology 1988, 61: 650-651. PMID: 3257840, DOI: 10.1016/0002-9149(88)90784-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultCoronary Artery BypassCoronary DiseaseHeartHeart VentriclesHumansMaleMyocardial ContractionStroke VolumeConceptsWall motion abnormalitiesVentricular dysfunctionLeft ventricularMotion abnormalitiesReversible wall motion abnormalitiesSevere coronary artery diseaseVentricular wall motion abnormalitiesIschemic ventricular dysfunctionReversible ventricular dysfunctionCoronary artery bypassCoronary artery diseasePeriod of ischemiaArtery bypassIschemic dysfunctionArtery diseaseHibernating myocardiumMyocardial infarctionMyocardial scarDysfunctionFibrous tissueRecent evidencePatientsComplete reversalAbnormalitiesRevascularizationThe Effect of Incremental Positive End-Expiratory Pressure on Right Ventricular Hemodynamics and Ejection Fraction.
Biondi JW, Schulman DS, Soufer R, Matthay RA, Hines RL, Kay HR, Barash PG. The Effect of Incremental Positive End-Expiratory Pressure on Right Ventricular Hemodynamics and Ejection Fraction. Anesthesia & Analgesia 1988, 67: 144. PMID: 3277479, DOI: 10.1213/00000539-198802000-00007.Peer-Reviewed Original ResearchConceptsH2O positive end-expiratory pressurePositive end-expiratory pressureRight ventricular end-diastolic volume indexRight ventricular end-systolic volume indexEnd-systolic volume indexRight ventricular ejection fractionEnd-expiratory pressureVentricular end-diastolic volume indexVentricular end-systolic volume indexIncremental positive end-expiratory pressureEnd-diastolic volume indexVentricular ejection fractionEjection fractionVolume indexRV end-systolic volume indexSystolic pressure-volume relationRight ventricular hemodynamicsRight ventricular functionRight ventricular contractilityRV contractilityRV hemodynamicsSystolic pressureVentricular functionVentricular contractilityPressure-volume relationEffect of positive end-expiratory pressure on right ventricular performance Importance of baseline right ventricular function
Schulman D, Biondi J, Matthay R, Barash P, Zaret B, Soufer R. Effect of positive end-expiratory pressure on right ventricular performance Importance of baseline right ventricular function. The American Journal Of Medicine 1988, 84: 57-67. PMID: 3276186, DOI: 10.1016/0002-9343(88)90009-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCardiac OutputFemaleHemodynamicsHumansIntensive Care UnitsMaleMiddle AgedMyocardial ContractionPositive-Pressure RespirationStroke VolumeConceptsRight ventricular ejection fractionBaseline right ventricular ejection fractionVentricular ejection fractionBaseline right ventricular functionRight ventricular functionEjection fractionContractile functionVentricular functionVentricular volumePositive end-expiratory pressure (PEEP) applicationSystolic pressure-volume relationPositive end-expiratory pressureRight ventricular contractile functionSystolic volume relationRight heart pressuresEffects of PEEPVentricular contractile functionEnd-expiratory pressureEnd-systolic volumeRight ventricular volumeH2O PEEPHeart pressuresPEEP levelsPressure-volume relationCardiac output