1998
Effects of thyroid hormone on the neonatal renal cortical Na+/H+ antiporter
Baum M, Dwarakanath V, Alpern R, Moe O. Effects of thyroid hormone on the neonatal renal cortical Na+/H+ antiporter. Kidney International 1998, 53: 1254-1258. PMID: 9573540, PMCID: PMC4131927, DOI: 10.1046/j.1523-1755.1998.00879.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAntithyroid AgentsFemaleHyperthyroidismHypothyroidismKidney CortexKidney Tubules, ProximalMaternal-Fetal ExchangePregnancyPropylthiouracilRatsRats, Sprague-DawleyRNA, MessengerSodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersSodium-Potassium-Exchanging ATPaseTriiodothyronineConceptsThyroid hormonesHyperthyroid neonatesNHE-3 protein abundanceNHE-3 mRNA abundanceDays of lifeLower ratesNeonatal proximal tubuleAntiporter activityHypothyroid neonatesHyperthyroid groupMaturational increaseProximal tubulesPostnatal increaseHyperthyroid ratsBicarbonate absorptionPmol/NeonatesHormonePotential roleBrush borderEuthyroidOne-thirdRatsMRNA abundanceApical membrane
1991
Chronic K depletion stimulates rat renal brush-border membrane Na-citrate cotransporter
Levi M, McDonald LA, Preisig PA, Alpern RJ. Chronic K depletion stimulates rat renal brush-border membrane Na-citrate cotransporter. American Journal Of Physiology 1991, 261: f767-f773. PMID: 1683169, DOI: 10.1152/ajprenal.1991.261.5.f767.Peer-Reviewed Original ResearchMeSH KeywordsAlkaline PhosphataseAlpha-GlucosidasesAnimalsCarrier ProteinsGamma-GlutamyltransferaseKidneyKineticsLeucyl AminopeptidaseMaleMicrovilliPotassium DeficiencyRatsRats, Inbred StrainsSodium-Potassium-Exchanging ATPase
1985
Amiloride inhibition of proximal tubular acidification
Howlin KJ, Alpern RJ, Rector FC. Amiloride inhibition of proximal tubular acidification. American Journal Of Physiology 1985, 248: f773-f778. PMID: 2988347, DOI: 10.1152/ajprenal.1985.248.6.f773.Peer-Reviewed Original ResearchConceptsProximal tubular acidificationLuminal amilorideBicarbonate absorptionX minTubular acidificationM amilorideSodium chloride absorptionLate proximal tubular fluidProximal tubular fluidPerfusion rateProximal acidificationVivo microperfusionTubular fluidKidney cortexChloride absorptionInhibition of acidificationPmol xAmilorideNonspecific inhibitionAmiloride inhibitionGreater inhibitionBrush border membrane vesiclesInhibitionGlucose effluxPotent inhibitor