2024
Ten Year Follow-up After Face Transplantation – a Single Center Retrospective Cohort Study
Huelsboemer L, Kauke-Navarro M, Boroumand S, Parikh N, Hosseini H, Yu C, Stögner V, Ko C, Perry B, Formica R, Hung P, Mahajan A, Azzi J, Murphy G, Pomahac B. Ten Year Follow-up After Face Transplantation – a Single Center Retrospective Cohort Study. American Journal Of Transplantation 2024 PMID: 39413877, DOI: 10.1016/j.ajt.2024.10.007.Peer-Reviewed Original ResearchChronic rejectionFace transplantationFollow-upSingle center retrospective cohort studyFunctional outcomesSensory returnAnalysis of functional outcomesMedian follow-upIncidence of malignancyMetabolic side effectsGraft rejection episodesComputed tomography angiogramRetrospective cohort studyEvidence of vasculopathyFollow-up periodLong-term outcomesYear follow-upFacial motor functionRejection episodesInfectious complicationsTransplant recipientsPatient ageGraft retentionMedical complicationsCohort studyThe role of C4d and donor specific antibodies in face and hand transplantation—a systematic review
Huelsboemer L, Moscarelli J, Dony A, Boroumand S, Kochen A, Knoedler L, Yu C, Hauc S, Stögner V, Formica R, Lian C, Murphy G, Pomahac B, Kauke-Navarro M. The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review. Frontiers In Transplantation 2024, 3: 1442006. PMID: 39291278, PMCID: PMC11405992, DOI: 10.3389/frtra.2024.1442006.Peer-Reviewed Original ResearchDonor-specific antibodiesSerum donor-specific antibodiesAntibody-mediated rejectionHigher rejection gradesVascularized composite allotransplantationC4d depositionRejection gradeCellular rejectionRejection episodesSpecific antibodiesDonor-specific antibody statusManagement of antibody-mediated rejectionFace transplantationAcute cellular rejectionAcute rejection episodesAssociated with high gradeTime of biopsyAntibody mediated rejectionFisher's exact testMann-Whitney U testSystematic review of electronic databasesMechanisms of rejectionSystematic reviewReview of electronic databasesC4d stainingD111. Ten year Follow up after Face Transplantation
Huelsboemer L, Kauke-Navarro M, Boroumand S, Parikh N, Hosseini H, Yu C, Stögner V, Ko C, Perry B, Formica R, Hung P, Mahajan A, Azzi J, Murphy G, Pomahac B. D111. Ten year Follow up after Face Transplantation. Plastic & Reconstructive Surgery Global Open 2024, 12: 120-121. PMCID: PMC11340540, DOI: 10.1097/01.gox.0001018916.83172.5e.Peer-Reviewed Original Research12. Functional Long-Term Outcome Of Eight Face Transplant Patients - A Single Center Study
Huelsboemer L, Stoegner V, Boroumand S, Parikh N, Hosseini H, Perry B, Formica R, Kauke-Navarro M, Pomahac B. 12. Functional Long-Term Outcome Of Eight Face Transplant Patients - A Single Center Study. Plastic & Reconstructive Surgery Global Open 2024, 12: 8-9. PMCID: PMC11041197, DOI: 10.1097/01.gox.0001015140.10439.0d.Peer-Reviewed Original ResearchThe gratitude paradox
Chisholm‐Burns M, Formica R. The gratitude paradox. Journal Of Internal Medicine 2024, 295: 712-714. PMID: 38575552, DOI: 10.1111/joim.13788.Peer-Reviewed Original ResearchImmunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes
Huelsboemer L, Boroumand S, Kochen A, Dony A, Moscarelli J, Hauc S, Stögner V, Formica R, Pomahac B, Kauke-Navarro M. Immunosuppressive strategies in face and hand transplantation: a comprehensive systematic review of current therapy regimens and outcomes. Frontiers In Transplantation 2024, 3: 1366243. PMID: 38993787, PMCID: PMC11235358, DOI: 10.3389/frtra.2024.1366243.Peer-Reviewed Original ResearchCMV infectionImmunosuppressive regimensImmunosuppressive strategiesTransplant recipientsIncidence of rejection episodesClinical CMV infectionTriple maintenance therapyIncidence of rejectionEpisodes of rejectionIndividualized immunosuppressive regimensEffective immunosuppressive therapySystematic reviewFace transplant patientsHand transplant recipientsHand transplantationFacial graftImmunosuppressive therapyMaintenance therapyRejection episodesFacial mucosaGraft lossGraft rejectionTherapy regimensTransplant patientsRenal failureUse of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians
Wiseman A, Alhamad T, Alloway R, Concepcion B, Cooper M, Formica R, Klein C, Kumar V, Leca N, Shihab F, Taber D, Mulnick S, Bushnell D, Hadi M, Bunnapradist S. Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians. Annals Of Transplantation 2024, 29: e943498-1-e943498-13. PMID: 38526543, PMCID: PMC10944009, DOI: 10.12659/aot.943498.Peer-Reviewed Original ResearchConceptsLCP-tacrolimusImmediate-release tacrolimusKidney transplantationFirst-line optionKidney transplant recipientsRandomized clinical trialsDe novo settingTacrolimus formulationReview available dataEvidence-based recommendationsTrough levelsOnce-dailyTransplant recipientsClinical decision-makingOptimal doseClinical trialsExpert cliniciansConsensus statementTransplant expertsStrength of evidenceClinical practiceKidneyTacrolimusDe novoDelphi consensus survey
2023
Evaluation of Opening Offers Early for Deceased Donor Kidneys at Risk of Nonutilization
Kilambi V, Barah M, Formica R, Friedewald J, Mehrotra S. Evaluation of Opening Offers Early for Deceased Donor Kidneys at Risk of Nonutilization. Clinical Journal Of The American Society Of Nephrology 2023, 19: 233-240. PMID: 37943856, PMCID: PMC10861110, DOI: 10.2215/cjn.0000000000000346.Peer-Reviewed Original ResearchUse of an LCP Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians
Wiseman A, Bunnapradist S, Alhamad T, Alloway R, Concepcion B, Cooper M, Formica R, Klein C, Kumar V, Leca N, Shihab F, Taber D, Mulnick S, Bushnell D, Hadi M. Use of an LCP Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians. Journal Of The American Society Of Nephrology 2023, 34: 1032-1033. DOI: 10.1681/asn.20233411s11032d.Peer-Reviewed Original ResearchPhysician Preferences when Selecting Candidates for Lower-Quality Kidney Offers
Sepulveda J, Mehrotra S, Yang J, Schantz K, Becker Y, Formica R, Ladner D, Kaufman D, Friedewald J. Physician Preferences when Selecting Candidates for Lower-Quality Kidney Offers. Clinical Journal Of The American Society Of Nephrology 2023, 18: 1599-1609. PMID: 37729938, PMCID: PMC10723918, DOI: 10.2215/cjn.0000000000000302.Peer-Reviewed Original ResearchConceptsCold ischemia timePanel reactive antibodyIschemia timeMarginal kidneysEjection fractionReactive antibodiesRecipient characteristicsPost-transplant survival scoreSignificant associationKidney Donor Profile IndexKarnofsky performance scoreSerum creatinine levelsHistory of diabetesLow-quality kidneysHLA mismatchesPerformance statusRecipient ageCreatinine levelsDiabetes statusHLA matchCirculatory deathKidney qualityYounger recipientsDonor ageDiscrete choice experimentAdvancing Face Transplantation: A Critical Analysis of Revisions and Long-Term Surgical Outcomes in 10 Cases
Mookerjee V, Kauke-Navarro M, Hauc S, Huelsboemer L, Formica R, Pomahac B. Advancing Face Transplantation: A Critical Analysis of Revisions and Long-Term Surgical Outcomes in 10 Cases. Plastic & Reconstructive Surgery 2023, 154: 577e-584e. PMID: 37699110, DOI: 10.1097/prs.0000000000011058.Peer-Reviewed Original ResearchMedical recordsLong-term surgical outcomesFace transplantationChronic allograft rejectionMedian time intervalLong-term outcomesComplex facial injuriesPatients' medical recordsFace transplantFace transplant recipientsAllograft rejectionTransplant recipientsSurgical revisionSurgical outcomesMajority of revisionsOperative reportsRevision surgeryProvider teamRetrospective analysisTEN casesFacial injuriesPeriorbital tissuesPatientsTransplantationMost interventionsThe National Organ Transplant Act Must Be Updated to Meet the Demands of Transplantation's Future
Formica R. The National Organ Transplant Act Must Be Updated to Meet the Demands of Transplantation's Future. Clinical Journal Of The American Society Of Nephrology 2023, 18: 554-556. PMID: 37016475, PMCID: PMC10278798, DOI: 10.2215/cjn.0000000000000139.Peer-Reviewed Original ResearchStakeholders’ perspectives on transplant metrics: the 2022 Scientific Registry of Transplant Recipients’ consensus conference
Snyder J, Schaffhausen C, Hart A, Axelrod D, Dils D, Formica R, Gaber A, Hunt H, Jones J, Mohan S, Patzer R, Pinney S, Ratner L, Slaker D, Stewart D, Stewart Z, Van Slyck S, Kasiske B, Hirose R, Israni A. Stakeholders’ perspectives on transplant metrics: the 2022 Scientific Registry of Transplant Recipients’ consensus conference. American Journal Of Transplantation 2023, 23: 875-890. PMID: 36958628, DOI: 10.1016/j.ajt.2023.03.012.Peer-Reviewed Original ResearchTreatment of De Novo Renal Transplant Recipients With Calcineurin Inhibitor–free, Belatacept Plus Everolimus–based Immunosuppression
Peddi V, Marder B, Gaite L, Oberholzer J, Goldberg R, Pearson T, Yang H, Allamassey L, Polinsky M, Formica R. Treatment of De Novo Renal Transplant Recipients With Calcineurin Inhibitor–free, Belatacept Plus Everolimus–based Immunosuppression. Transplantation Direct 2023, 9: e1419. PMID: 36700062, PMCID: PMC9820789, DOI: 10.1097/txd.0000000000001419.Peer-Reviewed Original ResearchBiopsy-proven acute rejection rateAcute rejection ratesAcute rejectionITT populationMycophenolate mofetilDe novo renal transplant recipientsBiopsy-proven acute rejectionDe novo renal transplantHigher acute rejection ratesNovo renal transplant recipientsRabbit antithymocyte globulin inductionCalcineurin inhibitor-based immunosuppressionAntithymocyte globulin inductionLymphocyte-depleting inductionGood renal functionPosttransplant lymphoproliferative disorderRenal transplant recipientsPhase 2 studyGlomerular filtration rateUnexpected adverse eventsEpstein-Barr virusCorticosteroid withdrawalGlobulin inductionGraft lossMaintenance regimenThe Unintended Consequences of Changes to the Organ Allocation Policy
Formica R, Schold J. The Unintended Consequences of Changes to the Organ Allocation Policy. Journal Of The American Society Of Nephrology 2023, 34: 14-16. PMID: 36719146, PMCID: PMC10101628, DOI: 10.1681/asn.0000000000000009.Peer-Reviewed Original Research
2022
Current Strategies to Enhance Opportunities for Patients with End Stage Kidney Disease to Receive a Kidney Transplant
Virmani S, Formica R. Current Strategies to Enhance Opportunities for Patients with End Stage Kidney Disease to Receive a Kidney Transplant. 2022, 83-88. DOI: 10.1007/978-3-031-11942-2_7.Peer-Reviewed Original ResearchA Composite End Point of Graft Status and eGFR at 1 Year to Improve the Scientific Registry of Transplant Recipients’ Five-Tier Rating System
Wang K, Deng Y, Stewart D, Formica R. A Composite End Point of Graft Status and eGFR at 1 Year to Improve the Scientific Registry of Transplant Recipients’ Five-Tier Rating System. Journal Of The American Society Of Nephrology 2022, 33: 1613-1624. PMID: 35537779, PMCID: PMC9342646, DOI: 10.1681/asn.2022010078.Peer-Reviewed Original ResearchConceptsComposite end pointTraditional end pointsTransplant programsEnd pointAllograft functionGraft survivalScientific RegistryFive-tier systemLong-term graft outcomeDonor graft survivalKidney transplant programAllograft failureAllograft survivalGraft outcomeTransplant recipientsGraft statusGraft failureEGFR differenceSRTR dataSurvival rateEGFRSurvivalRegistryMeaningful differencesConcept study
2021
It Is Time for Patient-Reported Outcome Measures to Be Included in the Approval Process for Solid Organ Transplant Medications
Formica R, Turgeon N. It Is Time for Patient-Reported Outcome Measures to Be Included in the Approval Process for Solid Organ Transplant Medications. Journal Of The American Society Of Nephrology 2021, 32: 2984-2986. PMID: 36734821, PMCID: PMC8638394, DOI: 10.1681/asn.2021081136.Peer-Reviewed Original ResearchImproving Transplant Program Performance Monitoring
Shepherd S, Formica R. Improving Transplant Program Performance Monitoring. Current Transplantation Reports 2021, 8: 293-300. DOI: 10.1007/s40472-021-00344-z.Peer-Reviewed Original Research
2020
The Development of a Comprehensive Multi-Institutional, Multi-Disciplinary Infrastructure for the Successful Implementation of a Robotic-Assisted Kidney Transplant (RAKT) Program
Haakinson D, Tzvetanov I, Turner A, Deshpande R, Formica R, Kulkarni S, Benedetti E, Mulligan D. The Development of a Comprehensive Multi-Institutional, Multi-Disciplinary Infrastructure for the Successful Implementation of a Robotic-Assisted Kidney Transplant (RAKT) Program. Journal Of The American College Of Surgeons 2020, 231: e224. DOI: 10.1016/j.jamcollsurg.2020.08.597.Peer-Reviewed Original Research