2000
Macaque blood‐derived antigen‐presenting cells elicit SIV‐specific immune responses
Zhu Y, Koo K, Bradshaw J, Sutton W, Kuller L, Bucala R, Anderson D, Mossman S, Villinger F, Haigwood N. Macaque blood‐derived antigen‐presenting cells elicit SIV‐specific immune responses. Journal Of Medical Primatology 2000, 29: 182-192. PMID: 11085581, DOI: 10.1034/j.1600-0684.2000.290312.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibody FormationAntigen-Presenting CellsAntigens, CDAntigens, CD34Antigens, ViralCells, CulturedDendritic CellsGenes, ReporterGreen Fluorescent ProteinsHumansImmunity, CellularImmunoglobulinsLuminescent ProteinsMacaca fascicularisMembrane GlycoproteinsMonocytesSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian immunodeficiency virusTransfectionTransplantation, AutologousConceptsMonocyte-derived dendritic cellsDendritic cellsAntigen-presenting cellsInterleukin-4Autologous monocyte-derived dendritic cellsSIV-specific immune responsesAutologous dendritic cellsDC marker CD83Macaque dendritic cellsGranulocyte-macrophage colonyMurine fibrocytesSIV vaccinesSIV antigensHumoral responseAntigen presentationImmune responseCharacteristic cellular morphologyDNA expression vectorsFibrocytesMacaca fascicularisSIVProtein expression plasmidsMacaquesExpression plasmidCells
1997
The Pathogenic Role of Macrophage Migration Inhibitory Factor in Immunologically Induced Kidney Disease in the Rat
Lan H, Bacher M, Yang N, Mu W, Nikolic-Paterson D, Metz C, Meinhardt A, Bucala R, Atkins R. The Pathogenic Role of Macrophage Migration Inhibitory Factor in Immunologically Induced Kidney Disease in the Rat. Journal Of Experimental Medicine 1997, 185: 1455-1466. PMID: 9126926, PMCID: PMC2196273, DOI: 10.1084/jem.185.8.1455.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntibody FormationCell Adhesion MoleculesGene ExpressionGlomerulonephritisHypersensitivity, DelayedIntercellular Adhesion Molecule-1Interleukin-1Macrophage Migration-Inhibitory FactorsMaleMiceNitric Oxide SynthaseRabbitsRatsRats, Sprague-DawleyRNA, MessengerSkinTime FactorsVascular Cell Adhesion Molecule-1ConceptsMacrophage migration inhibitory factorControl antibody-treated animalsDelayed-type hypersensitivity responseAnti-MIF treatmentAntibody-treated animalsMigration inhibitory factorAdhesion molecule-1Hypersensitivity responseKidney diseaseLeukocytic infiltrationHistological damageCrescentic anti-glomerular basement membrane (GBM) glomerulonephritisMolecule-1Skin delayed-type hypersensitivity responseInducible nitric oxide synthase (iNOS) expressionAnti-glomerular basement membrane glomerulonephritisInhibitory factorVascular cell adhesion molecule-1Nitric oxide synthase expressionIntercellular adhesion molecule-1Cell adhesion molecule-1Rabbit anti-rat GBM serumProgressive renal injuryRenal function impairmentAnti-GBM glomerulonephritis
1996
MIF re-discovered: Pituitary hormone and glucocorticoid-induced regulator of cytokine production
Bucala R. MIF re-discovered: Pituitary hormone and glucocorticoid-induced regulator of cytokine production. Cytokine & Growth Factor Reviews 1996, 7: 19-24. PMID: 8864351, DOI: 10.1016/1359-6101(96)00008-1.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibody FormationCytokinesGlucocorticoidsHumansInflammationMacrophage Migration-Inhibitory FactorsModels, MolecularPituitary HormonesConceptsMacrophage migration inhibitory factorAssociation of MIFT cell-derived factorsCounter-regulatory hormonesPrimary immune responseMigration inhibitory factorCell-derived factorSource of infectionAnterior pituitary cell lineFirst cytokine activitiesLymph nodesCytokine productionGlucocorticoid actionPituitary cell lineImmune responsePituitary hormonesInflammatory sitesCytokine activityHost responseImmune systemInhibitory factorInhibitory effectTissue invasionProtein mediatorsRandom migration
1983
Characterization of antisera to the addition product formed by the nonenzymatic reaction of 16α-hydroxyestrone with albumin
Bucala R, Cerami A. Characterization of antisera to the addition product formed by the nonenzymatic reaction of 16α-hydroxyestrone with albumin. Molecular Immunology 1983, 20: 1289-1292. PMID: 6656775, DOI: 10.1016/0161-5890(83)90159-1.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusLupus erythematosusAutoimmune diseasesAlpha-hydroxyestroneHigh-titre antiseraLack of specificityCross-reactivity analysisPhenolic A-ringElevated levelsCharacterization of antiseraLow molar substitutionOHEAntiserumImmunochemical analysisHigh specificityAlbuminHigh affinity