2022
CD74 as a regulator of transcription in normal B cells
David K, Friedlander G, Pellegrino B, Radomir L, Lewinsky H, Leng L, Bucala R, Becker-Herman S, Shachar I. CD74 as a regulator of transcription in normal B cells. Cell Reports 2022, 41: 111572. PMID: 36323260, DOI: 10.1016/j.celrep.2022.111572.Peer-Reviewed Original ResearchConceptsMacrophage migration inhibitory factorNormal B cellsB cellsCytokine macrophage migration inhibitory factorRegulators of transcriptionChronic lymphocytic leukemia cellsMigration inhibitory factorNovel therapeutic pathwaysInhibition of transcriptionLymphocytic leukemia cellsTumor suppressor geneTranscriptional regulatorsTranscription factorsTherapeutic pathwaysCLL cellsFuture treatmentIntracellular domainOncogenic transformationMalignant cellsInhibitory factorRegulatory functionsPromoter areaLeukemia cellsTranscriptionGenes
1994
Differential expression of the small inducible cytokines GRO α and GROβ by synovial fibroblasts in chronic arthritis: Possible role in growth regulation
Hogan M, Sherry B, Ritchlin C, Fabre M, Winchester R, Cerami A, Bucala R. Differential expression of the small inducible cytokines GRO α and GROβ by synovial fibroblasts in chronic arthritis: Possible role in growth regulation. Cytokine 1994, 6: 61-69. PMID: 8003635, DOI: 10.1016/1043-4666(94)90009-4.Peer-Reviewed Original ResearchMeSH KeywordsActinsArthritis, RheumatoidBase SequenceCells, CulturedChemokine CXCL1Chemokines, CXCChemotactic FactorsConsensus SequenceCytokinesDNA PrimersFibroblastsGene ExpressionGrowth SubstancesHumansIntercellular Signaling Peptides and ProteinsInterleukin-8Molecular Sequence DataPolymerase Chain ReactionRNA, MessengerSulfur RadioisotopesSynovial MembraneTranscription, GeneticConceptsSynovial fibroblastsGRO alphaChronic arthritisRheumatoid synoviaSynovial fibroblast cell lineGRO betaPro-inflammatory statePro-inflammatory activityRheumatoid arthritisChronic inflammationConnective tissue responseRheumatoid synoviumInflammatory cytokinesRate of proliferationSynovial pannusCytokine activationGRO gammaMetalloproteinase activityArthritisSynoviaGrowth factorConstitutive expressionGrowth dysregulationTissue responseCell lines