2005
Advanced Glycosylation of LDL: Role in Oxidative Modification and Diabetic Complications
Bucala R, Makita Z, Cerami A, Vlassara H, Koschinsky T. Advanced Glycosylation of LDL: Role in Oxidative Modification and Diabetic Complications. 2005, 286-291. DOI: 10.1533/9781845698393.4.286.Peer-Reviewed Original ResearchTransition metal ionsAmine-containing phospholipidsRedox reactionsMetal ionsFree metalFacile mechanismOxidative modificationOxidationLipid oxidationApoprotein componentsMoietyGlycosylationAcid oxidationIonsAbsorbanceReactionModificationMetalsAGE moietiesFluorescencePhospholipidsPropertiesAdvanced glycosylationImmunochemical propertiesFormation
1986
Structure of lysine adducts with 16α-hydroxyestrone and cortisol
Bucala R, Ulrich P, Chait B, Bencsath F, Cerami A. Structure of lysine adducts with 16α-hydroxyestrone and cortisol. The Journal Of Steroid Biochemistry And Molecular Biology 1986, 25: 127-133. PMID: 3091937, DOI: 10.1016/0022-4731(86)90291-8.Peer-Reviewed Original ResearchConceptsSchiff baseReduced Schiff baseStructure of lysineCovalent addition productsPresence of NaCNBH3Schiff base adductsHeyns rearrangementNucleophilic additionAddition productsBase adductsEpsilon-amino groupLysine derivativesStructural analysisAdductsLysine residuesReactionNaCNBH3MoietyCarbonylAminesCompoundsSynthesisMoleculesProductsLysine