Efficient Scavenging of Fatty Acid Oxidation Products by Aminoguanidine
Al-Abed Y, Bucala R. Efficient Scavenging of Fatty Acid Oxidation Products by Aminoguanidine. Chemical Research In Toxicology 1997, 10: 875-879. PMID: 9282836, DOI: 10.1021/tx970035l.Peer-Reviewed Original ResearchConceptsLow-density lipoprotein levelsAdvanced glycation end productsGlycation end productsMechanism of actionVascular wall componentsLipoprotein levelsLipoprotein metabolismOxidative stressPharmacological inhibitorsFatty acid oxidation productsHuman subjectsToxic effectsAminoguanidineOxidative damageNormal pathwayReactive aldehydesRecent studiesPotential interactionsDamaging effectsVivoTissue constituentsEnd productsAtherogenesisLipid oxidationMalondialdehyde