Macrophage migration inhibitory factor production by Leydig cells: evidence for a role in the regulation of testicular function
Meinhardt A, Bacher M, McFarlane J, Metz C, Seitz J, Hedger M, de Kretser D, Bucala R. Macrophage migration inhibitory factor production by Leydig cells: evidence for a role in the regulation of testicular function. Endocrinology 1996, 137: 5090-5095. DOI: 10.1210/en.137.11.5090.Peer-Reviewed Original ResearchLeydig cellsMacrophage migration inhibitory factorSeminiferous tubulesRat testisHeads of elongated spermatidsRegulation of testicular functionAdult rat seminiferous tubulesTM3 Leydig cell lineTesticular functionLeydig cell steroidogenesis in vitroPeritubular myoid cellsLeydig cell lineAdult rat testisRat seminiferous tubulesPurified Leydig cellsMIF messenger RNAExpression of MIF messenger RNAMessenger RNALong-term hypophysectomized ratsIntracellular macrophage migration inhibitory factorMigration inhibitory factor productionProduct of activated T lymphocytesMurine macrophage migration inhibitory factorElongated spermatidsMacrophage migration inhibitory factor production