2024
Autonomic Reactivity to Mental Stress is Associated with Cardiovascular Mortality
Shah A, Vaccarino V, Moazzami K, Almuwaqqat Z, Garcia M, Ward L, Elon L, Ko Y, Sun Y, Pearce B, Raggi P, Bremner J, Lampert R, Quyyumi A, Shah A. Autonomic Reactivity to Mental Stress is Associated with Cardiovascular Mortality. European Heart Journal Open 2024, oeae086. DOI: 10.1093/ehjopen/oeae086.Peer-Reviewed Original ResearchHazard ratioCardiovascular diseaseHigher CVD mortality riskAssociated with CVD mortalityHeart rate variabilityCardiovascular disease risk factorsCVD mortality riskCardiovascular disease mortalityCardiovascular disease deathsCardiovascular disease outcomesCause-specific survival modelsAssociated with cardiovascular mortalityAll-cause mortalityCVD causeAssociated with HRCVD mortalityMental stress testMeasure of autonomic dysfunctionMortality riskAssess autonomic functionAutonomic dysfunctionCardiovascular mortalityStable cardiovascular diseaseRisk factorsPooled cohortStress-Induced Autonomic Dysfunction is Associated With Mental Stress–Induced Myocardial Ischemia in Patients With Coronary Artery Disease
Osei J, Vaccarino V, Wang M, Shah A, Lampert R, Li L, Ko Y, Pearce B, Kutner M, Garcia E, Piccinelli M, Raggi P, Bremner J, Quyyumi A, Sun Y, Ahmed H, Haddad G, Daaboul O, Roberts T, Stefanos L, Correia L, Shah A. Stress-Induced Autonomic Dysfunction is Associated With Mental Stress–Induced Myocardial Ischemia in Patients With Coronary Artery Disease. Circulation Cardiovascular Imaging 2024, 17: e016596. PMID: 38868952, PMCID: PMC11187646, DOI: 10.1161/circimaging.124.016596.Peer-Reviewed Original ResearchConceptsMental stress-induced myocardial ischemiaLow heart rate variabilityAssociated with MSIMICoronary artery diseaseAssociated with higher oddsStable coronary artery diseaseStress-induced myocardial ischemiaAutonomic dysfunctionLow-frequency heart rate variabilityArtery diseaseHeart rate variabilityHigher oddsHigher heart rate variabilityResponse to stressIndicator of autonomic dysfunctionMyocardial ischemiaSpeech stressorAssociated with adverse cardiovascular outcomesMultivariate logistic regression modelAssociation of autonomic dysfunctionAdverse cardiovascular outcomesLogistic regression modelsBlack participantsHolter monitoringClinical factorsHeart Rate Variability, Deceleration Capacity of Heart Rate, and Death: A Veteran Twins Study
Huang M, Shah A, Lampert R, Bliwise D, Johnson D, Clifford G, Sloan R, Goldberg J, Ko Y, Da Poian G, Perez‐Alday E, Almuwaqqat Z, Shah A, Garcia M, Young A, Moazzami K, Bremner J, Vaccarino V. Heart Rate Variability, Deceleration Capacity of Heart Rate, and Death: A Veteran Twins Study. Journal Of The American Heart Association 2024, 13: e032740. PMID: 38533972, PMCID: PMC11179789, DOI: 10.1161/jaha.123.032740.Peer-Reviewed Original ResearchConceptsLow-frequency heart rate variabilityHazard of deathAssociated with reduced mortality riskMortality riskMultivariable Cox frailty modelsHeart rate variabilityAssociated with decreased hazard of deathNational Death IndexDeceleration capacityAssociated with lower hazardWithin-pair analysesTwin studiesCox frailty modelsHazard ratio of deathRatio of deathDeceleration capacity of heart rateAssociated with decreased hazardDeath IndexHeart rateAll-cause deathHazard ratioFrequency domain heart rate variabilityStrong associationsHousehold food insecurity is associated with greater autonomic dysfunction testing score in Latinos with type 2 diabetes
Bermúdez-Millán A, Feinn R, Lampert R, Pérez-Escamilla R, Segura-Pérez S, Wagner J. Household food insecurity is associated with greater autonomic dysfunction testing score in Latinos with type 2 diabetes. PLOS ONE 2024, 19: e0297681. PMID: 38394186, PMCID: PMC10889858, DOI: 10.1371/journal.pone.0297681.Peer-Reviewed Original ResearchConceptsDiastolic blood pressureAutonomic function testsAutonomic nervous systemType 2 diabetesHousehold food insecurityDysfunction indexFunction testsHigher diastolic blood pressureAverage diastolic blood pressureAssociated with ANS dysfunctionU.S. Household Food Security Survey ModuleHousehold Food Security Survey ModuleFood Security Survey ModuleBaseline supineFood insecuritySustained handgripBenefit health outcomesLow-income LatinosANS dysfunctionScore 0Improve food accessHandgrip testInsulin useBlood pressureHeart rate variability
2017
Food Insecurity, Glycemic Control, and Heart Rate Variability among Latinos with Type 2 Diabetes
Bermúdez‐Millán A, Pérez‐Escamilla R, Lampert R, Segura‐Pérez S, Damio G, Chhabra J, Wagner J. Food Insecurity, Glycemic Control, and Heart Rate Variability among Latinos with Type 2 Diabetes. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.lb432.Peer-Reviewed Original ResearchHeart rate variabilityGlycemic controlRate variabilityPoor cardiovascular outcomesAmerican Diabetes AssociationType 2 diabetesNon-invasive measureAmbulatory ECG monitorCardiovascular outcomesFood insecurityDiabetes AssociationDiabetes outcomesLower SDNNSecondary data analysisAutonomic statusType 2HRV indicesR intervalHealth disparitiesMinority HealthSocioeconomic statusSocial adversityBaseline dataNational InstituteManagement trials