Granulomatous Adenohypophysitis after Interferon and Ribavirin Therapy
Tebben P, Atkinson J, Scheithauer B, Erickson D. Granulomatous Adenohypophysitis after Interferon and Ribavirin Therapy. Endocrine Practice 2007, 13: 169-175. PMID: 17490932, DOI: 10.4158/ep.13.2.169.Peer-Reviewed Case Reports and Technical NotesConceptsInterferon alfa-2bGranulomatous hypophysitisMagnetic resonance imagingRibavirin therapyAlfa-2bOptic chiasmMultiple anterior pituitary hormone deficiencyTreated with interferon alfa-2bRadiographic evidenceAnterior pituitary hormone deficienciesFollow-up magnetic resonance imagingSupraphysiologic doses of prednisoneCase of granulomatous hypophysitisElevated angiotensin-converting enzyme levelDiffuse pituitary enlargementInterferon-induced thyroiditisAngiotensin-converting enzyme levelsHigh-dose glucocorticoidsResonance imagingPituitary hormone deficiencyEvidence of thyroiditisSymptoms of thyrotoxicosisDoses of glucocorticoidsDose of prednisonePhysiological doses of glucocorticoids